Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT

Tsu Chi Cheng, Nan-Tsing Chiu, Ting Yu Su, Yi Fei He, Wei Tse Yang, Yu-Hua Dean Fang

研究成果: Conference contribution

摘要

Lung Cancer is a leading cause of death worldwide, and about 85% of lung cancer is non-small cell lung cancer (NSCLC). The staging of lymph nodes in NSCLC patients is extremely important because respective stages require different treatments. FDG-PET/CT is a gold standard for lymph node metastasis staging of NSCLC. However, the results of discriminating lymph node staging on 18F-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) / computed tomography (CT) still needs improvement. In addition to the traditional image parameters of FDG-PET/CT such as standardized uptake value (SUV), there are many other parameters available from FDG-PET/CT images, for example, the lymphatic drainage pathway. Other than this, texture analysis which distinguishes subtle difference can also be a way to define lymph node staging. For the purpose of a better accuracy on lymph node metastasis diagnosis on NSCLC patient in FDG-PET/CT, this research developed a computer-aided diagnosis (CAD) system to improve the diagnostic efficiency, which achieved 88.056% accuracy.

原文English
主出版物標題International Forum on Medical Imaging in Asia 2019
編輯Jong Hyo Kim, Hiroshi Fujita, Feng Lin
發行者SPIE
ISBN(電子)9781510627758
DOIs
出版狀態Published - 2019 一月 1
事件International Forum on Medical Imaging in Asia 2019 - Singapore, Singapore
持續時間: 2019 一月 72019 一月 9

出版系列

名字Proceedings of SPIE - The International Society for Optical Engineering
11050
ISSN(列印)0277-786X
ISSN(電子)1996-756X

Conference

ConferenceInternational Forum on Medical Imaging in Asia 2019
國家Singapore
城市Singapore
期間19-01-0719-01-09

指紋

Positron Emission Tomography
Positron emission tomography
Metastasis
lymphatic system
Lung Cancer
Computed Tomography
metastasis
Glucose
glucose
lungs
Tomography
positrons
tomography
cancer
Cells
Cell
Vertex of a graph
Computer aided diagnosis
Computer-aided Diagnosis
Texture Analysis

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

引用此文

Cheng, T. C., Chiu, N-T., Su, T. Y., He, Y. F., Yang, W. T., & Fang, Y-H. D. (2019). Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT. 於 J. H. Kim, H. Fujita, & F. Lin (編輯), International Forum on Medical Imaging in Asia 2019 [110500Z] (Proceedings of SPIE - The International Society for Optical Engineering; 卷 11050). SPIE. https://doi.org/10.1117/12.2521510
Cheng, Tsu Chi ; Chiu, Nan-Tsing ; Su, Ting Yu ; He, Yi Fei ; Yang, Wei Tse ; Fang, Yu-Hua Dean. / Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT. International Forum on Medical Imaging in Asia 2019. 編輯 / Jong Hyo Kim ; Hiroshi Fujita ; Feng Lin. SPIE, 2019. (Proceedings of SPIE - The International Society for Optical Engineering).
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title = "Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT",
abstract = "Lung Cancer is a leading cause of death worldwide, and about 85{\%} of lung cancer is non-small cell lung cancer (NSCLC). The staging of lymph nodes in NSCLC patients is extremely important because respective stages require different treatments. FDG-PET/CT is a gold standard for lymph node metastasis staging of NSCLC. However, the results of discriminating lymph node staging on 18F-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) / computed tomography (CT) still needs improvement. In addition to the traditional image parameters of FDG-PET/CT such as standardized uptake value (SUV), there are many other parameters available from FDG-PET/CT images, for example, the lymphatic drainage pathway. Other than this, texture analysis which distinguishes subtle difference can also be a way to define lymph node staging. For the purpose of a better accuracy on lymph node metastasis diagnosis on NSCLC patient in FDG-PET/CT, this research developed a computer-aided diagnosis (CAD) system to improve the diagnostic efficiency, which achieved 88.056{\%} accuracy.",
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Cheng, TC, Chiu, N-T, Su, TY, He, YF, Yang, WT & Fang, Y-HD 2019, Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT. 於 JH Kim, H Fujita & F Lin (編輯), International Forum on Medical Imaging in Asia 2019., 110500Z, Proceedings of SPIE - The International Society for Optical Engineering, 卷 11050, SPIE, International Forum on Medical Imaging in Asia 2019, Singapore, Singapore, 19-01-07. https://doi.org/10.1117/12.2521510

Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT. / Cheng, Tsu Chi; Chiu, Nan-Tsing; Su, Ting Yu; He, Yi Fei; Yang, Wei Tse; Fang, Yu-Hua Dean.

International Forum on Medical Imaging in Asia 2019. 編輯 / Jong Hyo Kim; Hiroshi Fujita; Feng Lin. SPIE, 2019. 110500Z (Proceedings of SPIE - The International Society for Optical Engineering; 卷 11050).

研究成果: Conference contribution

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AU - Cheng, Tsu Chi

AU - Chiu, Nan-Tsing

AU - Su, Ting Yu

AU - He, Yi Fei

AU - Yang, Wei Tse

AU - Fang, Yu-Hua Dean

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Lung Cancer is a leading cause of death worldwide, and about 85% of lung cancer is non-small cell lung cancer (NSCLC). The staging of lymph nodes in NSCLC patients is extremely important because respective stages require different treatments. FDG-PET/CT is a gold standard for lymph node metastasis staging of NSCLC. However, the results of discriminating lymph node staging on 18F-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) / computed tomography (CT) still needs improvement. In addition to the traditional image parameters of FDG-PET/CT such as standardized uptake value (SUV), there are many other parameters available from FDG-PET/CT images, for example, the lymphatic drainage pathway. Other than this, texture analysis which distinguishes subtle difference can also be a way to define lymph node staging. For the purpose of a better accuracy on lymph node metastasis diagnosis on NSCLC patient in FDG-PET/CT, this research developed a computer-aided diagnosis (CAD) system to improve the diagnostic efficiency, which achieved 88.056% accuracy.

AB - Lung Cancer is a leading cause of death worldwide, and about 85% of lung cancer is non-small cell lung cancer (NSCLC). The staging of lymph nodes in NSCLC patients is extremely important because respective stages require different treatments. FDG-PET/CT is a gold standard for lymph node metastasis staging of NSCLC. However, the results of discriminating lymph node staging on 18F-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) / computed tomography (CT) still needs improvement. In addition to the traditional image parameters of FDG-PET/CT such as standardized uptake value (SUV), there are many other parameters available from FDG-PET/CT images, for example, the lymphatic drainage pathway. Other than this, texture analysis which distinguishes subtle difference can also be a way to define lymph node staging. For the purpose of a better accuracy on lymph node metastasis diagnosis on NSCLC patient in FDG-PET/CT, this research developed a computer-aided diagnosis (CAD) system to improve the diagnostic efficiency, which achieved 88.056% accuracy.

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PB - SPIE

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Cheng TC, Chiu N-T, Su TY, He YF, Yang WT, Fang Y-HD. Diagnosis of lymph node metastasis in non-small-cell lung cancer (NSCLC) patient on F-18-FDG PET/CT. 於 Kim JH, Fujita H, Lin F, 編輯, International Forum on Medical Imaging in Asia 2019. SPIE. 2019. 110500Z. (Proceedings of SPIE - The International Society for Optical Engineering). https://doi.org/10.1117/12.2521510