Dielectrophoresis of Caenorhabditis elegans

Han Sheng Chuang, David M. Raizen, Annesia Lamb, Nooreen Dabbish, Haim H. Bau

研究成果: Article同行評審

39 引文 斯高帕斯(Scopus)

摘要

We demonstrate for the first time the dielectrophoretic trapping and manipulation of a whole animal, the nematode Caenorhabditis elegans. We studied the effect of the electric field on the nematode as a function of field intensity and frequency. We identified a range of electric field intensities and frequencies that trap worms without apparent adverse effect on their viability. Worms tethered by dielectrophoresis (DEP) exhibit behavioral responses to blue light, indicating that at least some of the nervous system functions are unimpaired by the electrical field. DEP is useful to dynamically tether nematodes, sort nematodes according to size, and separate dead worms from live ones.

原文English
頁(從 - 到)599-604
頁數6
期刊Lab on a Chip
11
發行號4
DOIs
出版狀態Published - 2011 2月 21

All Science Journal Classification (ASJC) codes

  • 生物工程
  • 生物化學
  • 一般化學
  • 生物醫學工程

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