Dynamic change of tetraspanin CD151 membrane protein expression in colorectal cancer patients

研究成果: Article

7 引文 斯高帕斯(Scopus)

摘要

Purpose: To measure the CD151 expression in colorectal cancer (CRC). Methods: CD151 expression was assessed in 179 CRC patients and 39 patients with hepatic liver metastasis. Results: High CD151 expression was observed in 48% of patients with early-stage CRC versus only 33% of patients with metastatic colon cancer. A higher level of tumor invasion status correlated with a decrease in CD151 expression. Metastatic stage and advanced tumor stage correlated with a decreased CD151 expression. Twenty-seven out of the 39-paired samples had high CD151 expression in liver metastasis sites. Conclusions: CD151 expression is decreased in patients with metastatic CRC.

原文English
頁(從 - 到)542-547
頁數6
期刊Cancer Investigation
29
發行號8
DOIs
出版狀態Published - 2011 十月 1

    指紋

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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