EBER-1 positive diffuse large cell lymphoma presenting as lupus nephritis

Ming Hsien Lin, Jeng Jong Huang, Tsai-Yun Chen, Fen Fen Chen, Kung-Chao Chang, Ming-Fei Liu, Wen Tsung Huang, Wu-Chou Su, Chao Jung Tsao

研究成果: Article

4 引文 斯高帕斯(Scopus)

摘要

Approximately one-third of membranous glomerulonephritis (MGN) cases in adults are associated with systemic diseases, including systemic lupus erythematosus (SLE) or malignancies. Malignancy-associated glomerulonephritis is rarely found in non-Hodgkin's lymphoma (NHL). Epstein-Barr virus (EBV) has been postulated to contribute to the pathogenesis of both SLE and NHL. We described a 37-year-old woman with nephrotic syndrome who presented with clinical features of SLE and renal-biopsy revealed lupus MGN. The patient also suffered from concomitant progressive lymphadenopathy and NHL (diffuse large B-cell type) was demonstrated by neck lymph node biopsy. Serologic studies demonstrated EBV infection and specific EBVantigens were present on lymph node and metastatic sites. We offer a discussion regarding the complex relationships between SLE, NHL, MGN and EBV.

原文English
頁(從 - 到)486-489
頁數4
期刊Lupus
12
發行號6
DOIs
出版狀態Published - 2003 七月 21

All Science Journal Classification (ASJC) codes

  • Rheumatology

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    Lin, M. H., Huang, J. J., Chen, T-Y., Chen, F. F., Chang, K-C., Liu, M-F., Huang, W. T., Su, W-C., & Tsao, C. J. (2003). EBER-1 positive diffuse large cell lymphoma presenting as lupus nephritis. Lupus, 12(6), 486-489. https://doi.org/10.1191/0961203303lu414cr