EBER-1 positive diffuse large cell lymphoma presenting as lupus nephritis

Ming Hsien Lin, Jeng Jong Huang, Tsai Yun Chen, Fen Fen Chen, Kong Chao Chang, Ming Fei Liu, Wen Tsung Huang, Wu Chou Su, Chao Jung Tsao

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)

摘要

Approximately one-third of membranous glomerulonephritis (MGN) cases in adults are associated with systemic diseases, including systemic lupus erythematosus (SLE) or malignancies. Malignancy-associated glomerulonephritis is rarely found in non-Hodgkin's lymphoma (NHL). Epstein-Barr virus (EBV) has been postulated to contribute to the pathogenesis of both SLE and NHL. We described a 37-year-old woman with nephrotic syndrome who presented with clinical features of SLE and renal-biopsy revealed lupus MGN. The patient also suffered from concomitant progressive lymphadenopathy and NHL (diffuse large B-cell type) was demonstrated by neck lymph node biopsy. Serologic studies demonstrated EBV infection and specific EBVantigens were present on lymph node and metastatic sites. We offer a discussion regarding the complex relationships between SLE, NHL, MGN and EBV.

原文English
頁(從 - 到)486-489
頁數4
期刊Lupus
12
發行號6
DOIs
出版狀態Published - 2003

All Science Journal Classification (ASJC) codes

  • 風濕病

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