Efficient determination of the epidermal optical properties using a diffusion model-based approach: Monte Carlo studies

Sheng Hao Tseng, Ming Feng Hou

研究成果: Article同行評審

4 引文 斯高帕斯(Scopus)

摘要

In our previous studies, we have shown that the diffusing probe geometry can be used in conjunction with a two-layer diffusion model to accurately recover the absorption and scattering properties of skin in vivo. By modifying the original design to the diffusing probe with planar source (DPPS) geometry, we have also demonstrated that the efficiency of the accompanying multilayer diffusion model is comparable to that of a standard semi-infinite diffusion model; thus, precise quantification of superficial tissue optical properties in real time using a diffusion model becomes possible. In this study, the performance of the DPPS diffusion model is evaluated using Monte Carlo simulations and phantom measurements. It is found that the DPPS geometry is advantageous over the conventional planar source illumination geometry in interrogating superficial volumes of samples. In addition, our simulation results have shown that the DPPS geometry is capable of accurately recovering the optical properties of 50-m thick epidermis and could be very useful in detecting cutaneous melanoma that has a radius as small as 250 m.

原文English
文章編號087007
期刊Journal of Biomedical Optics
16
發行號8
DOIs
出版狀態Published - 2011 8月

All Science Journal Classification (ASJC) codes

  • 電子、光磁材料
  • 生物材料
  • 原子與分子物理與光學
  • 生物醫學工程

指紋

深入研究「Efficient determination of the epidermal optical properties using a diffusion model-based approach: Monte Carlo studies」主題。共同形成了獨特的指紋。

引用此