Efficient synthesis of 2-(N-Substituted)-2-imidazolines and 2-(N-Substituted)-1,4,5, 6-tetrahydropyrimidines

Wai Ming Kan, Shih Hsun Lin, Ching Yuh Chern

研究成果: Article同行評審

7 引文 斯高帕斯(Scopus)

摘要

A general method for the preparation of 2-(N-Substituted)-2-imidazolines and 2-(N-Substituted)-1,4,5,6-tetrahydropyrimidines is described. These heterocycles can be synthesized from their respective anilines with 2-chloro-2-imidazoline or 2-chloro-1,4,5,6-tetrahydropyrimidine, generated in situ from imidazolidin-2-one and tetrahydropyrimidin-2(1H)-one activated by dimethyl chlorophosphate, in good to excellent yields.

原文English
頁(從 - 到)2633-2639
頁數7
期刊Synthetic Communications
35
發行號20
DOIs
出版狀態Published - 2005

All Science Journal Classification (ASJC) codes

  • 有機化學

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