Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

Ping Ching Wu; Jiu Yao Wang; Wen Lung Wang; Chia Yuan Chang; Chia Hung Huang; Kun Lin Yang; Jui Cheng Chang; Chih Li Lilian Hsu; Shih Yao Chen; Ting Mao Chou; Wen Shuo Kuo

doi:10.1039/c7nr06836k

Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

Ping Ching Wu, Jiu Yao Wang, Wen Lung Wang, Chia Yuan Chang, Chia Hung Huang, Kun Lin Yang, Jui Cheng Chang, Chih Li Lilian Hsu, Shih Yao Chen, Ting Mao Chou, Wen Shuo Kuo

研究成果: Article › 同行評審

38 引文斯高帕斯（Scopus）

摘要

Nitrogen-doped graphene quantum dot (N-GQD) nanomaterials conjugated with polyethylenimine (PEI)-polystyrene sulfonate (PSS)-anti-epidermal growth factor receptor (Ab_EGFR) antibody (N-GQD-PEI-PSS-Ab_EGFR) demonstrated impressive two-photon properties and stability, signifying that they can serve as an effective two-photon contrast agent in two-photon bioimaging. Furthermore, they provided high intensity, brightness, and signal-to-noise ratios at an ultra-low two-photon excitation (TPE) power level in an observation extending to a deep, three-dimensional depth.

原文	English
頁（從 - 到）	109-117
頁數	9
期刊	Nanoscale
卷	10
發行號	1
DOIs	https://doi.org/10.1039/c7nr06836k
出版狀態	Published - 2018 1月 7

All Science Journal Classification (ASJC) codes

一般材料科學

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10.1039/c7nr06836k

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title = "Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers",

abstract = "Nitrogen-doped graphene quantum dot (N-GQD) nanomaterials conjugated with polyethylenimine (PEI)-polystyrene sulfonate (PSS)-anti-epidermal growth factor receptor (AbEGFR) antibody (N-GQD-PEI-PSS-AbEGFR) demonstrated impressive two-photon properties and stability, signifying that they can serve as an effective two-photon contrast agent in two-photon bioimaging. Furthermore, they provided high intensity, brightness, and signal-to-noise ratios at an ultra-low two-photon excitation (TPE) power level in an observation extending to a deep, three-dimensional depth.",

author = "Wu, {Ping Ching} and Wang, {Jiu Yao} and Wang, {Wen Lung} and Chang, {Chia Yuan} and Huang, {Chia Hung} and Yang, {Kun Lin} and Chang, {Jui Cheng} and Hsu, {Chih Li Lilian} and Chen, {Shih Yao} and Chou, {Ting Mao} and Kuo, {Wen Shuo}",

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AU - Wu, Ping Ching

AU - Wang, Jiu Yao

AU - Wang, Wen Lung

AU - Chang, Chia Yuan

AU - Huang, Chia Hung

AU - Yang, Kun Lin

AU - Chang, Jui Cheng

AU - Hsu, Chih Li Lilian

AU - Chen, Shih Yao

AU - Chou, Ting Mao

AU - Kuo, Wen Shuo

PY - 2018/1/7

Y1 - 2018/1/7

N2 - Nitrogen-doped graphene quantum dot (N-GQD) nanomaterials conjugated with polyethylenimine (PEI)-polystyrene sulfonate (PSS)-anti-epidermal growth factor receptor (AbEGFR) antibody (N-GQD-PEI-PSS-AbEGFR) demonstrated impressive two-photon properties and stability, signifying that they can serve as an effective two-photon contrast agent in two-photon bioimaging. Furthermore, they provided high intensity, brightness, and signal-to-noise ratios at an ultra-low two-photon excitation (TPE) power level in an observation extending to a deep, three-dimensional depth.

AB - Nitrogen-doped graphene quantum dot (N-GQD) nanomaterials conjugated with polyethylenimine (PEI)-polystyrene sulfonate (PSS)-anti-epidermal growth factor receptor (AbEGFR) antibody (N-GQD-PEI-PSS-AbEGFR) demonstrated impressive two-photon properties and stability, signifying that they can serve as an effective two-photon contrast agent in two-photon bioimaging. Furthermore, they provided high intensity, brightness, and signal-to-noise ratios at an ultra-low two-photon excitation (TPE) power level in an observation extending to a deep, three-dimensional depth.

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Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

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