Eighteen-Year Follow-Up of a Retrospective Study of HLA Antibody on Kidney Graft Survival

P. C. Lee, M. Ozawa, C. J. Hung, Y. J. Lin, S. S. Chang, T. C. Chou

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)

摘要

An increasing number of studies have demonstrated adverse graft survival in patients who have anti-HLA antibodies, whether preformed or developed posttransplantation. This retrospective study used Lambda antigen tray-mixed (LAT-M) screening and Luminex HLA class I and II specificity assay to re-examine the impact of pretransplantation HLA antibody on long-term graft survival. In this study, pretransplantation sera from 288 renal patients were tested using the enzyme-linked immunosorbent assay (ELISA) method, LAT-M. Among the 234 of the patients who did not have pretransplantation antibodies, 85% enjoyed 5-year functional graft survival, 76% 10-year functional graft survival, and 56% 15-year functional graft survival. The corresponding functional graft survival for the 54 patients who tested HLA antibody-positive was 65%, 53%, and 28%, respectively (P = .0021).

原文English
頁(從 - 到)121-123
頁數3
期刊Transplantation Proceedings
41
發行號1
DOIs
出版狀態Published - 2009 1月

All Science Journal Classification (ASJC) codes

  • 手術
  • 移植

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