Endometriosis: Disease pathophysiology and the role of prostaglandins

Meng Hsing Wu, Yutaka Shoji, Pei Chin Chuang, Shaw Jenq Tsai

研究成果: Review article同行評審

82 引文 斯高帕斯(Scopus)


Endometriosis is considered to be a polygenic disease with a complex, multifactorial aetiology that affects about 10% of women in the reproductive age. Women with endometriosis have symptoms that include chronic pelvic pain, dysmenorrhoea and dyspareunia, significantly reducing their quality of life. Endometriosis is also the primary cause of infertility in women, with the prevalence rate ranging from 20% to 50%. The high prevalence and severe outcomes of this disease have made it a major public health concern in modern society. Currently, the mechanism(s) responsible for the initiation and promotion of this disease remains obscure. In this review, we focus on the expression, regulation and action of prostaglandins in the cellular and molecular mechanisms that contribute to the development and/or maintenance of endometriosis.

頁(從 - 到)1-20
期刊Expert Reviews in Molecular Medicine
出版狀態Published - 2007 1月

All Science Journal Classification (ASJC) codes

  • 分子醫學
  • 分子生物學


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