Engineering Biomaterials with Micro/Nanotechnologies for Cell Reprogramming

Jun Fang, Yuan Yu Hsueh, Jennifer Soto, Wujin Sun, Jinqiang Wang, Zhen Gu, Ali Khademhosseini, Song Li

研究成果: Review article同行評審

8 引文 斯高帕斯(Scopus)

摘要

Cell reprogramming is a revolutionized biotechnology that offers a powerful tool to engineer cell fate and function for regenerative medicine, disease modeling, drug discovery, and beyond. Leveraging advances in biomaterials and micro/nanotechnologies can enhance the reprogramming performance in vitro and in vivo through the development of delivery strategies and the control of biophysical and biochemical cues. In this review, we present an overview of the state-of-the-art technologies for cell reprogramming and highlight the recent breakthroughs in engineering biomaterials with micro/nanotechnologies to improve reprogramming efficiency and quality. Finally, we discuss future directions and challenges for reprogramming technologies and clinical translation.

原文English
頁(從 - 到)1296-1318
頁數23
期刊ACS nano
14
發行號2
DOIs
出版狀態Published - 2020 二月 25

All Science Journal Classification (ASJC) codes

  • 材料科學(全部)
  • 工程 (全部)
  • 物理與天文學 (全部)

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