Engineering microbes for direct fermentation of cellulose to bioethanol

Hao Liu, Jianliang Sun, Jo-Shu Chang, Pratyoosh Shukla

研究成果: Review article

9 引文 (Scopus)

摘要

Consolidated bioprocessing (CBP) by micro-organisms is desired for efficient conversion of lignocellulosic biomass to bioethanol fuels. Potential candidates have been discovered, including cellulolytic bacteria and filamentous fungi. Genetic and metabolic manipulation of these organisms further promotes their fermentation capacities and the ethanol tolerance. In addition, Saccharomyces cerevisiae and several other yeasts were genetically modified to express recombinant cellulases in media or display them on the cell surface for CBP of cellulose. To compensate the insufficient capacity of a single strain, various microbial consortia have also been developed. In this article, we reviewed the recent advances in CBP microbes and focused on the efforts in strain improvement employing genetic engineering.

原文English
頁(從 - 到)1089-1105
頁數17
期刊Critical Reviews in Biotechnology
38
發行號7
DOIs
出版狀態Published - 2018 十月 3

指紋

Microbial Consortia
Cellulases
Genetic Engineering
Cellulose
Biomass
Fermentation
Saccharomyces cerevisiae
Fungi
Ethanol
Yeasts
Bacteria

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology

引用此文

Liu, Hao ; Sun, Jianliang ; Chang, Jo-Shu ; Shukla, Pratyoosh. / Engineering microbes for direct fermentation of cellulose to bioethanol. 於: Critical Reviews in Biotechnology. 2018 ; 卷 38, 編號 7. 頁 1089-1105.
@article{9846dfe147544112b4332f4bd362f8fb,
title = "Engineering microbes for direct fermentation of cellulose to bioethanol",
abstract = "Consolidated bioprocessing (CBP) by micro-organisms is desired for efficient conversion of lignocellulosic biomass to bioethanol fuels. Potential candidates have been discovered, including cellulolytic bacteria and filamentous fungi. Genetic and metabolic manipulation of these organisms further promotes their fermentation capacities and the ethanol tolerance. In addition, Saccharomyces cerevisiae and several other yeasts were genetically modified to express recombinant cellulases in media or display them on the cell surface for CBP of cellulose. To compensate the insufficient capacity of a single strain, various microbial consortia have also been developed. In this article, we reviewed the recent advances in CBP microbes and focused on the efforts in strain improvement employing genetic engineering.",
author = "Hao Liu and Jianliang Sun and Jo-Shu Chang and Pratyoosh Shukla",
year = "2018",
month = "10",
day = "3",
doi = "10.1080/07388551.2018.1452891",
language = "English",
volume = "38",
pages = "1089--1105",
journal = "Critical Reviews in Biotechnology",
issn = "0738-8551",
publisher = "Informa Healthcare",
number = "7",

}

Engineering microbes for direct fermentation of cellulose to bioethanol. / Liu, Hao; Sun, Jianliang; Chang, Jo-Shu; Shukla, Pratyoosh.

於: Critical Reviews in Biotechnology, 卷 38, 編號 7, 03.10.2018, p. 1089-1105.

研究成果: Review article

TY - JOUR

T1 - Engineering microbes for direct fermentation of cellulose to bioethanol

AU - Liu, Hao

AU - Sun, Jianliang

AU - Chang, Jo-Shu

AU - Shukla, Pratyoosh

PY - 2018/10/3

Y1 - 2018/10/3

N2 - Consolidated bioprocessing (CBP) by micro-organisms is desired for efficient conversion of lignocellulosic biomass to bioethanol fuels. Potential candidates have been discovered, including cellulolytic bacteria and filamentous fungi. Genetic and metabolic manipulation of these organisms further promotes their fermentation capacities and the ethanol tolerance. In addition, Saccharomyces cerevisiae and several other yeasts were genetically modified to express recombinant cellulases in media or display them on the cell surface for CBP of cellulose. To compensate the insufficient capacity of a single strain, various microbial consortia have also been developed. In this article, we reviewed the recent advances in CBP microbes and focused on the efforts in strain improvement employing genetic engineering.

AB - Consolidated bioprocessing (CBP) by micro-organisms is desired for efficient conversion of lignocellulosic biomass to bioethanol fuels. Potential candidates have been discovered, including cellulolytic bacteria and filamentous fungi. Genetic and metabolic manipulation of these organisms further promotes their fermentation capacities and the ethanol tolerance. In addition, Saccharomyces cerevisiae and several other yeasts were genetically modified to express recombinant cellulases in media or display them on the cell surface for CBP of cellulose. To compensate the insufficient capacity of a single strain, various microbial consortia have also been developed. In this article, we reviewed the recent advances in CBP microbes and focused on the efforts in strain improvement employing genetic engineering.

UR - http://www.scopus.com/inward/record.url?scp=85045153372&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045153372&partnerID=8YFLogxK

U2 - 10.1080/07388551.2018.1452891

DO - 10.1080/07388551.2018.1452891

M3 - Review article

C2 - 29631429

AN - SCOPUS:85045153372

VL - 38

SP - 1089

EP - 1105

JO - Critical Reviews in Biotechnology

JF - Critical Reviews in Biotechnology

SN - 0738-8551

IS - 7

ER -