TY - JOUR
T1 - Enhanced production of high-value polyunsaturated fatty acids (PUFAs) from potential thraustochytrid Aurantiochytrium sp.
AU - Chauhan, Ajeet Singh
AU - Patel, Anil Kumar
AU - Chen, Chiu Wen
AU - Chang, Jo Shu
AU - Michaud, Philippe
AU - Dong, Cheng Di
AU - Singhania, Reeta Rani
N1 - Funding Information:
AKP would like to acknowledge the NSTC, Taiwan for funding support (Ref. No. NSTC 111-2222-E-992-006).
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2023/2
Y1 - 2023/2
N2 - Due to growing health concerns, the urban population is utterly inclined towards a healthy lifestyle and incorporated nutritional food supplements to lower common health risks. The ω-3 and ω-6 PUFAs consumption is increasing, hence alternative commercial production is essentially developed. The microbial source is an emerging platform to overcome the global demand for omega PUFAs. Marine oleaginous protist Aurantiochytrium sp. found a potential source to produce substantial DHA and SFA. The objective of the present research was to enhance the PUFA yield by optimizing maximum tolerable glucose concentration with a suitable nitrogen ratio (10:1). The maximum lipid and DHA yield and content were determined 4.30, 1.34 g/L, and 62.4, 33.49 % of total biomass and lipid at 30 g/L glucose respectively, which is one of among highest reported, however relative PUFA was maximum 46.97 % (DHA) in total lipid at 10 g/L glucose. Remaining 42–53.6 % SFA could be used for biodiesel.
AB - Due to growing health concerns, the urban population is utterly inclined towards a healthy lifestyle and incorporated nutritional food supplements to lower common health risks. The ω-3 and ω-6 PUFAs consumption is increasing, hence alternative commercial production is essentially developed. The microbial source is an emerging platform to overcome the global demand for omega PUFAs. Marine oleaginous protist Aurantiochytrium sp. found a potential source to produce substantial DHA and SFA. The objective of the present research was to enhance the PUFA yield by optimizing maximum tolerable glucose concentration with a suitable nitrogen ratio (10:1). The maximum lipid and DHA yield and content were determined 4.30, 1.34 g/L, and 62.4, 33.49 % of total biomass and lipid at 30 g/L glucose respectively, which is one of among highest reported, however relative PUFA was maximum 46.97 % (DHA) in total lipid at 10 g/L glucose. Remaining 42–53.6 % SFA could be used for biodiesel.
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U2 - 10.1016/j.biortech.2022.128536
DO - 10.1016/j.biortech.2022.128536
M3 - Article
C2 - 36581232
AN - SCOPUS:85145303950
SN - 0960-8524
VL - 370
JO - Agricultural Wastes
JF - Agricultural Wastes
M1 - 128536
ER -