TY - JOUR
T1 - Enhancing the flow efficiency of micropumping devices using a PDMS biomimetic diversion system
AU - Lai, Hsin Yi
AU - Kang, Jing Hao
N1 - Publisher Copyright:
© 2022 Taylor & Francis Group, LLC.
PY - 2024
Y1 - 2024
N2 - In this paper, a biomimetic diversion structure was proposed based on the contraction and expansion behavior of the heart valve, which was placed in the micropump of the circular chamber. The micropump is composed of a PZT-4A actuator and a PDMS diversion structure, whose role is to behave as both a control flow rate and a flow field rectification. The weak form "fluid solid coupling" modeling method is used to simulate the flow field characteristics of the micropump, and then the geometric parameters of the PDMS diversion structure is redesigned to achieve the flow rate basic requirements (3.5 ml min−1). The research results confirm that the proposed micropump has the best pump efficiency (3.34%) at a backpressure of 25 cmH2O and a flow rate of 1.79 mL min−1. In addition, the net flow rate was assessed over a range of operating frequencies (200–900 Hz, in 50 Hz increments). The maximum flow rate is approximately 3.53 ml min−1 at a resonance frequency of 700 Hz. This indicates that the presented micropump has an advantage in drug delivery applications owing to its frequency regulation characteristics, and that the release rate of drug delivery can be easily controlled to maintain therapeutic efficacy.
AB - In this paper, a biomimetic diversion structure was proposed based on the contraction and expansion behavior of the heart valve, which was placed in the micropump of the circular chamber. The micropump is composed of a PZT-4A actuator and a PDMS diversion structure, whose role is to behave as both a control flow rate and a flow field rectification. The weak form "fluid solid coupling" modeling method is used to simulate the flow field characteristics of the micropump, and then the geometric parameters of the PDMS diversion structure is redesigned to achieve the flow rate basic requirements (3.5 ml min−1). The research results confirm that the proposed micropump has the best pump efficiency (3.34%) at a backpressure of 25 cmH2O and a flow rate of 1.79 mL min−1. In addition, the net flow rate was assessed over a range of operating frequencies (200–900 Hz, in 50 Hz increments). The maximum flow rate is approximately 3.53 ml min−1 at a resonance frequency of 700 Hz. This indicates that the presented micropump has an advantage in drug delivery applications owing to its frequency regulation characteristics, and that the release rate of drug delivery can be easily controlled to maintain therapeutic efficacy.
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U2 - 10.1080/15376494.2022.2128121
DO - 10.1080/15376494.2022.2128121
M3 - Article
AN - SCOPUS:85141014570
SN - 1537-6494
VL - 31
SP - 948
EP - 958
JO - Mechanics of Advanced Materials and Structures
JF - Mechanics of Advanced Materials and Structures
IS - 4
ER -