Europium doped Gd2O3 and FeCo nanoparticles for biomedical application

K. Zhang, T. Holloway, M. Bahoura, A. K. Pradhan, R. Prabakaran, J. Pradhan, S. Smith, J. C. Hall, G. T. Ramesh, D. R. Sahu, J. L. Huang

研究成果: Conference contribution

13 引文 斯高帕斯(Scopus)

摘要

Nanometer-sized particles have novel optical, electronic, magnetic or structural properties and are currently under intense development for application in cancer, cardiovascular diseases, and degenerative neurological disorders such as alzheimer's disease. Targeted nanoparticle drugs offer significant advantages in improving cancer therapeutic efficacy and simultaneously reducing drug toxicity. We report here the synthesis, characterization and toxicity test of FeCo and Eu: Gd 2O 3 nanoparticles. Chemical routes, such ad coprecipitation and sol-gel techniques were used for the synthesis of the nanoparticles, and the surface of the nanoparticles was coated with silica. Structural and microstructural studies reveal that both type of nanoparticles 20 nm in size with very narrow size distribution. These nanoparticles demonstrate strong magnetic and optical properties at room temperature. Toxicity test shows that FeCo nanoparticles are very toxic, however toxicity decreases when the nanoparticles were coated with a thin layer of silica. However toxicity decreases when the nanoparticles were coated with a thin layer of silica. However, both uncoated and coated Eu:Gd 2O 3 nanoparticles show significantly reduced toxicity. Our results suggest that these nanoparticles are useful for biomedical applications. The detail of the results will be presented.

原文English
主出版物標題Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009
DOIs
出版狀態Published - 2009 六月 15
事件Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009 - San Diego, CA, United States
持續時間: 2009 三月 92009 三月 11

出版系列

名字Proceedings of SPIE - The International Society for Optical Engineering
7291
ISSN(列印)0277-786X

Other

OtherNanosensors, Biosensors, and Info-Tech Sensors and Systems 2009
國家United States
城市San Diego, CA
期間09-03-0909-03-11

    指紋

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

引用此

Zhang, K., Holloway, T., Bahoura, M., Pradhan, A. K., Prabakaran, R., Pradhan, J., Smith, S., Hall, J. C., Ramesh, G. T., Sahu, D. R., & Huang, J. L. (2009). Europium doped Gd2O3 and FeCo nanoparticles for biomedical application. 於 Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009 [729104] (Proceedings of SPIE - The International Society for Optical Engineering; 卷 7291). https://doi.org/10.1117/12.817306