Fabrication of cellhydroxyapatite nanocrystal composites assisted with layer-by-layer nanometer-sized extracellular matrix films on individual stem cells

Sushmita Saha, Takashi Yoshikai, Chun Yen Liu, Michiya Matsusaki, Xuebin B. Yang, Mitsuru Akashi

研究成果: Article同行評審

2 引文 斯高帕斯(Scopus)

摘要

The ability to control cell function is one of the challenges for cell-based therapy in regenerative medicine. In this study, we describe a novel method to fabricate cellhydroxyapatite (HAp) nanocrystal composites to modulate cellular microenvironment. By preparation of layer-by-layer nanometer-sized extracellular matrix films onto cell surfaces, HAp nanocrystals were fabricated onto cell surfaces without cytotoxicity. This technology can modulate cellular functions such as adhesion, growth, and differentiation.

原文English
頁(從 - 到)1714-1716
頁數3
期刊Chemistry Letters
44
發行號12
DOIs
出版狀態Published - 2015

All Science Journal Classification (ASJC) codes

  • 化學 (全部)

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