Failure of Thymidine Kinase-Negative Herpes Simplex Virus to Reactivate from Latency following Efficient Establishment

Shih Heng Chen, Angela Pearson, Donald M. Coen, Shun Hua Chen

研究成果: Article

32 引文 斯高帕斯(Scopus)

摘要

Thymidine kinase-negative mutants of herpes simplex virus did not reactivate from latency in mouse trigeminal ganglia, even when their latent viral loads were comparable to those that permitted reactivation by wild-type virus. Thus, reduced establishment of latency does not suffice to account for the failure to reactivate.

原文English
頁(從 - 到)520-523
頁數4
期刊Journal of Virology
78
發行號1
DOIs
出版狀態Published - 2004 一月

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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