TY - JOUR
T1 - First naturally occurring homoacridone-flavanone dimers from Glycosmis parviflora
AU - Ito, Chihiro
AU - Matsui, Takuya
AU - Mamiya, Kaname
AU - Wu, Tian Shung
AU - Itoigawa, Masataka
N1 - Publisher Copyright:
© 2024 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2024
Y1 - 2024
N2 - The structures of flavacitropones A (1)-B (2), which are new homoacridone-flavanone dimers from Glycosmis parviflora (Sims) Kurz. (Rutaceae), were elucidated by spectroscopic studies. Flavacitropone A (1) was evaluated for its biological effects on cytotoxicity and release of histamine and TNF-α in 2,4-dinitrophenyl-human serum albumin-stimulated RBL-2H3 cells (rat basophilic cell line). The compound downregulated TNF-α release, but not histamine release.
AB - The structures of flavacitropones A (1)-B (2), which are new homoacridone-flavanone dimers from Glycosmis parviflora (Sims) Kurz. (Rutaceae), were elucidated by spectroscopic studies. Flavacitropone A (1) was evaluated for its biological effects on cytotoxicity and release of histamine and TNF-α in 2,4-dinitrophenyl-human serum albumin-stimulated RBL-2H3 cells (rat basophilic cell line). The compound downregulated TNF-α release, but not histamine release.
UR - https://www.scopus.com/pages/publications/85206100597
UR - https://www.scopus.com/pages/publications/85206100597#tab=citedBy
U2 - 10.1080/14786419.2024.2412844
DO - 10.1080/14786419.2024.2412844
M3 - Article
C2 - 39381938
AN - SCOPUS:85206100597
SN - 1478-6419
JO - Natural Product Research
JF - Natural Product Research
ER -