Flavonoids from Andrographis viscosula

Yerra Koteswara Rao, Amooru Gangaiah Damu, Alahari Janardhan Rao, Shanmuganathan Venkatesan, Ping Chung Kuo, Chunduri Venkata Rao, Tian Shung Wu

研究成果: Article

11 引文 斯高帕斯(Scopus)


Phytochemical investigation of the whole plant of Andrographis viscosula has led to the isolation of three new 2′-oxygenated flavonoids, (2R)-5-hydroxy-7,2′,3′-trimethoxyflavanone (1), 7,2′,5′- trimethoxyflavone (2), 5,7,2′,3′-tetramethoxyflavone (3), and eight known flavones, 5,7,2′-trimethoxyflavone (4), 5,7,2′,4′, 5′-pentamethoxyflavone (5), echioidinin (6), 5,2′,6′- trihydroxy-7-methoxyflavone (7), 5-hydroxy-7,2′-dimethoxyflavone (8), echioidin (9), echioidinin 5-O-glucoside (10), and 5,2′,6′- trihydroxy-7-methoxyflavone 2′-O-glucoside (11). The structures of 1-11 were elucidated by physical and spectral methods, including extensive 2D NMR studies. The presence of 2′-oxygenated flavonoids is apparently restricted to Andrographis species in Acanthaceae. Therefore, 2′-oxygenated flavonoids are regarded as chemotaxonomic markers of Andrographis genus in the Acanthaceae family.

頁(從 - 到)1374-1376
期刊Chemical and Pharmaceutical Bulletin
出版狀態Published - 2003 十二月 1

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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    Rao, Y. K., Damu, A. G., Rao, A. J., Venkatesan, S., Kuo, P. C., Rao, C. V., & Wu, T. S. (2003). Flavonoids from Andrographis viscosula. Chemical and Pharmaceutical Bulletin, 51(12), 1374-1376. https://doi.org/10.1248/cpb.51.1374