Frequency multiplexed intensity modulated diffuse reflectance system for quantification of tissue and arterial oxygen saturation

Po Jian Liang, Sheng Hao Tseng

研究成果: Conference contribution

摘要

Pulse oximeter has been a widely used instrument in hospitals or household for measuring arterial oxygen saturation value. Its annual global market value has exceeded USD 1 billion and is still growing. There are two main shortcomings in most pulse oximeters on the market: 1. database based algorithm limits the range of precision, and 2. incapable of measuring tissue oxygen saturation related to local tissue oxygen exchange condition. We developed a 3-wavelength frequency multiplexed intensity modulated diffuse reflectance system in which the modulation frequencies of the 3 light sources are different so that the light reflectance at the 3 wavelengths can be collected by the detector simultaneously. This allows us achieving determination of absorption and reduced scattering coefficients at the 3 wavelengths of the exactly same instant of time and this can lead to accurate quantification of tissue and arterial oxygen saturations. This technique works in conjunction with a photon diffusion equation and does not need to build a database in advance to calculate arterial oxygen saturation. In addition, capability of this system in measuring tissue oxygen saturation would facilitate swift monitoring of local tissue blood circulation.

原文English
主出版物標題European Conference on Biomedical Optics, ECBO_2019
發行者OSA - The Optical Society
ISBN(電子)9781557528209
DOIs
出版狀態Published - 2019 一月 1
事件European Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
持續時間: 2019 六月 232019 六月 25

出版系列

名字Optics InfoBase Conference Papers
Part F142-ECBO 2019

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO_2019
國家Netherlands
城市Munich
期間19-06-2319-06-25

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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