Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011

Le Phan Kim Thoa; Pai Shan Chiang; Truong Huu Khanh; Shu Ting Luo; Tran Ngoc Hanh Dan; Ya Fang Wang; Tang Chi Thuong; Wan Yu Chung; Nguyen Thanh Hung; Jen Ren Wang; Le Nguyen Thanh Nhan; Le Quoc Thinh; Ih Jen Su; Than Duc Dung; Min Shi Lee

doi:10.1371/journal.pone.0069895

Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011

Le Phan Kim Thoa, Pai Shan Chiang, Truong Huu Khanh, Shu Ting Luo, Tran Ngoc Hanh Dan, Ya Fang Wang, Tang Chi Thuong, Wan Yu Chung, Nguyen Thanh Hung, Jen Ren Wang, Le Nguyen Thanh Nhan, Le Quoc Thinh, Ih Jen Su, Than Duc Dung, Min Shi Lee

醫學檢驗生物技術學系

研究成果: Article › 同行評審

33 引文斯高帕斯（Scopus）

摘要

Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.

原文	English
文章編號	e69895
期刊	PloS one
卷	8
發行號	7
DOIs	https://doi.org/10.1371/journal.pone.0069895
出版狀態	Published - 2013 7月 29

All Science Journal Classification (ASJC) codes

多學科

存取文件

10.1371/journal.pone.0069895

其它文件與鏈接

引用此

Thoa, L. P. K., Chiang, P. S., Khanh, T. H., Luo, S. T., Dan, T. N. H., Wang, Y. F., Thuong, T. C., Chung, W. Y., Hung, N. T., Wang, J. R., Nhan, L. N. T., Thinh, L. Q., Su, I. J., Dung, T. D., & Lee, M. S. (2013). Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011. PloS one, 8(7), 文章 e69895. https://doi.org/10.1371/journal.pone.0069895

@article{15e9107de366497a8ade9c2e99c66c2f,

title = "Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011",

abstract = "Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.",

author = "Thoa, {Le Phan Kim} and Chiang, {Pai Shan} and Khanh, {Truong Huu} and Luo, {Shu Ting} and Dan, {Tran Ngoc Hanh} and Wang, {Ya Fang} and Thuong, {Tang Chi} and Chung, {Wan Yu} and Hung, {Nguyen Thanh} and Wang, {Jen Ren} and Nhan, {Le Nguyen Thanh} and Thinh, {Le Quoc} and Su, {Ih Jen} and Dung, {Than Duc} and Lee, {Min Shi}",

year = "2013",

month = jul,

day = "29",

doi = "10.1371/journal.pone.0069895",

language = "English",

volume = "8",

journal = "PloS one",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "7",

}

TY - JOUR

T1 - Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011

AU - Thoa, Le Phan Kim

AU - Chiang, Pai Shan

AU - Khanh, Truong Huu

AU - Luo, Shu Ting

AU - Dan, Tran Ngoc Hanh

AU - Wang, Ya Fang

AU - Thuong, Tang Chi

AU - Chung, Wan Yu

AU - Hung, Nguyen Thanh

AU - Wang, Jen Ren

AU - Nhan, Le Nguyen Thanh

AU - Thinh, Le Quoc

AU - Su, Ih Jen

AU - Dung, Than Duc

AU - Lee, Min Shi

PY - 2013/7/29

Y1 - 2013/7/29

N2 - Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.

AB - Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.

UR - http://www.scopus.com/inward/record.url?scp=84880769448&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880769448&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0069895

DO - 10.1371/journal.pone.0069895

M3 - Article

C2 - 23922846

AN - SCOPUS:84880769448

SN - 1932-6203

VL - 8

JO - PloS one

JF - PloS one

IS - 7

M1 - e69895

ER -

Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011

摘要

All Science Journal Classification (ASJC) codes

存取文件

其它文件與鏈接

指紋

引用此