Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011

Le Phan Kim Thoa, Pai Shan Chiang, Truong Huu Khanh, Shu Ting Luo, Tran Ngoc Hanh Dan, Ya Fang Wang, Tang Chi Thuong, Wan Yu Chung, Nguyen Thanh Hung, Jen Ren Wang, Le Nguyen Thanh Nhan, Le Quoc Thinh, Ih Jen Su, Than Duc Dung, Min Shi Lee

研究成果: Article

26 引文 斯高帕斯(Scopus)

摘要

Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.

原文English
文章編號e69895
期刊PloS one
8
發行號7
DOIs
出版狀態Published - 2013 七月 29

    指紋

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

引用此

Thoa, L. P. K., Chiang, P. S., Khanh, T. H., Luo, S. T., Dan, T. N. H., Wang, Y. F., Thuong, T. C., Chung, W. Y., Hung, N. T., Wang, J. R., Nhan, L. N. T., Thinh, L. Q., Su, I. J., Dung, T. D., & Lee, M. S. (2013). Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011. PloS one, 8(7), [e69895]. https://doi.org/10.1371/journal.pone.0069895