Genomic and proteomic analysis of mammary tumors arising in transgenic mice

Lu Xie, Baogang J. Xu, Agnieszka E. Gorska, Yu Shyr, Sarah A. Schwartz, Nikki Cheng, Shawn Levy, Brian Bierie, Richard M. Caprioli, Harold L. Moses

研究成果: Article同行評審

10 引文 斯高帕斯(Scopus)

摘要

Transforming growth factor-β (TGF-β) is the prototype of a large family of signaling molecules. TGF-β signaling profoundly influences tumor development as demonstrated in several engineered mouse models. The present study was designed to identify differences by cDNA microarray and MALDI-TOF MS analyses in mammary carcinomas with and without TGF-β signaling. The results demonstrate a significant potential for combination of profiling technologies to further understand the molecular mechanisms of breast cancer.

原文English
頁(從 - 到)2088-2098
頁數11
期刊Journal of Proteome Research
4
發行號6
DOIs
出版狀態Published - 2005 11月

All Science Journal Classification (ASJC) codes

  • 一般化學
  • 生物化學

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