Gestational diabetes and central pontine myelinolysis with quadriplegia: A case report

研究成果: Article同行評審

10 引文 斯高帕斯(Scopus)


Central pontine myelinolysis (CPM) has been reported in women with severe hyperemesis gravidarum-induced hyponatremia followed by rapid correction. Gestational diabetes with adipsia complicated by acute hypernatremia resulting in CPM has never been reported. Here is a case of a disabled female who presented with polydipsia, polyuria, seizures, fetal death in utero, hyperglycemia, and hyper-osmolar hypernatremia on her 31st gestational week. The dead fetus was delivered and the patient's plasma glucose and sodium were later stabilized. When the patient developed quadriplegia and respiratory failure 5 days later, brain magnetic resonance imaging showed central pontine and extra-pontine myelinolysis. Gestational diabetes complicated by hyper-osmolar crisis may cause fetal death and severe neurologic sequela. Early recognition and delivery of the fetus and placenta may improve the electrolyte and fluid imbalance.

頁(從 - 到)728-731
期刊Journal of Maternal-Fetal and Neonatal Medicine
出版狀態Published - 2010 7月

All Science Journal Classification (ASJC) codes

  • 兒科、圍產兒和兒童健康
  • 婦產科


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