Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling

Dongeun Huh, Hsien-Hung Wei, O. D. Kripfgans, J. B. Fowlkes, J. B. Grotberg, S. Takayama

研究成果: Conference contribution

9 引文 (Scopus)

摘要

Describes a new type of gravity-driven polymeric microfluidic cell sorter developed for low-power, low-cost, and rapid cell separation. The device takes advantage of size-based differential migration of cells/particles in flows where widening of flow streamlines amplifies the separation between sample particles. We studied the migration and separation of polystyrene microbeads, red blood cells, and perfluorocarbon droplets used for ultrasound imaging and therapy having different sizes in the novel cell sorter. Compared to other conventional cell separation systems, microHYCS reduces power and cost requirements, and is advantageous for the development of easy-to-use sample separation and diagnostics tools.

原文English
主出版物標題2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings
編輯David Beebe, Andre Dittmar
發行者Institute of Electrical and Electronics Engineers Inc.
頁面466-469
頁數4
ISBN(電子)0780374800, 9780780374805
DOIs
出版狀態Published - 2002 一月 1
事件2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Madison, United States
持續時間: 2002 五月 22002 五月 4

出版系列

名字2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings

Other

Other2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology
國家United States
城市Madison
期間02-05-0202-05-04

指紋

Cell Separation
Gravitation
Cell Size
Fluorocarbons
Costs and Cost Analysis
Microfluidics
Polystyrenes
Microspheres
Cell Movement
Ultrasonography
Erythrocytes
Equipment and Supplies
Therapeutics

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Microbiology (medical)

引用此文

Huh, D., Wei, H-H., Kripfgans, O. D., Fowlkes, J. B., Grotberg, J. B., & Takayama, S. (2002). Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling. 於 D. Beebe, & A. Dittmar (編輯), 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings (頁 466-469). [1002375] (2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MMB.2002.1002375
Huh, Dongeun ; Wei, Hsien-Hung ; Kripfgans, O. D. ; Fowlkes, J. B. ; Grotberg, J. B. ; Takayama, S. / Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling. 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings. 編輯 / David Beebe ; Andre Dittmar. Institute of Electrical and Electronics Engineers Inc., 2002. 頁 466-469 (2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings).
@inproceedings{b5bb1f24bc174f52ba5679df549285e8,
title = "Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling",
abstract = "Describes a new type of gravity-driven polymeric microfluidic cell sorter developed for low-power, low-cost, and rapid cell separation. The device takes advantage of size-based differential migration of cells/particles in flows where widening of flow streamlines amplifies the separation between sample particles. We studied the migration and separation of polystyrene microbeads, red blood cells, and perfluorocarbon droplets used for ultrasound imaging and therapy having different sizes in the novel cell sorter. Compared to other conventional cell separation systems, microHYCS reduces power and cost requirements, and is advantageous for the development of easy-to-use sample separation and diagnostics tools.",
author = "Dongeun Huh and Hsien-Hung Wei and Kripfgans, {O. D.} and Fowlkes, {J. B.} and Grotberg, {J. B.} and S. Takayama",
year = "2002",
month = "1",
day = "1",
doi = "10.1109/MMB.2002.1002375",
language = "English",
series = "2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "466--469",
editor = "David Beebe and Andre Dittmar",
booktitle = "2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings",
address = "United States",

}

Huh, D, Wei, H-H, Kripfgans, OD, Fowlkes, JB, Grotberg, JB & Takayama, S 2002, Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling. 於 D Beebe & A Dittmar (編輯), 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings., 1002375, 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings, Institute of Electrical and Electronics Engineers Inc., 頁 466-469, 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology, Madison, United States, 02-05-02. https://doi.org/10.1109/MMB.2002.1002375

Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling. / Huh, Dongeun; Wei, Hsien-Hung; Kripfgans, O. D.; Fowlkes, J. B.; Grotberg, J. B.; Takayama, S.

2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings. 編輯 / David Beebe; Andre Dittmar. Institute of Electrical and Electronics Engineers Inc., 2002. p. 466-469 1002375 (2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings).

研究成果: Conference contribution

TY - GEN

T1 - Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling

AU - Huh, Dongeun

AU - Wei, Hsien-Hung

AU - Kripfgans, O. D.

AU - Fowlkes, J. B.

AU - Grotberg, J. B.

AU - Takayama, S.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Describes a new type of gravity-driven polymeric microfluidic cell sorter developed for low-power, low-cost, and rapid cell separation. The device takes advantage of size-based differential migration of cells/particles in flows where widening of flow streamlines amplifies the separation between sample particles. We studied the migration and separation of polystyrene microbeads, red blood cells, and perfluorocarbon droplets used for ultrasound imaging and therapy having different sizes in the novel cell sorter. Compared to other conventional cell separation systems, microHYCS reduces power and cost requirements, and is advantageous for the development of easy-to-use sample separation and diagnostics tools.

AB - Describes a new type of gravity-driven polymeric microfluidic cell sorter developed for low-power, low-cost, and rapid cell separation. The device takes advantage of size-based differential migration of cells/particles in flows where widening of flow streamlines amplifies the separation between sample particles. We studied the migration and separation of polystyrene microbeads, red blood cells, and perfluorocarbon droplets used for ultrasound imaging and therapy having different sizes in the novel cell sorter. Compared to other conventional cell separation systems, microHYCS reduces power and cost requirements, and is advantageous for the development of easy-to-use sample separation and diagnostics tools.

UR - http://www.scopus.com/inward/record.url?scp=84964622066&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964622066&partnerID=8YFLogxK

U2 - 10.1109/MMB.2002.1002375

DO - 10.1109/MMB.2002.1002375

M3 - Conference contribution

AN - SCOPUS:84964622066

T3 - 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings

SP - 466

EP - 469

BT - 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings

A2 - Beebe, David

A2 - Dittmar, Andre

PB - Institute of Electrical and Electronics Engineers Inc.

ER -

Huh D, Wei H-H, Kripfgans OD, Fowlkes JB, Grotberg JB, Takayama S. Gravity-driven microhydrodynamics-based cell sorter (microHYCS) for rapid, inexpensive, and efficient cell separation and size-profiling. 於 Beebe D, Dittmar A, 編輯, 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2002. p. 466-469. 1002375. (2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings). https://doi.org/10.1109/MMB.2002.1002375