Gut microbiota and pediatric obesity/non-alcoholic fatty liver disease

Yao Jong Yang, Yen Hsuan Ni

研究成果: Review article同行評審

10 引文 斯高帕斯(Scopus)


Huge amount microorganisms resides in human intestine, and many contribute to the maturation and homeostasis of immune system. The diversity of gut ecology are affected by the gestational age, delivery type, feeding sources, and antibiotics use in neonates. Recent studies pointed out that disturbance of gut microbiota, so called dysbiosis, could result in several pediatric diseases including obesity, non-alcoholic fatty liver disease (NAFLD), metabolic syndromes, allergic diseases, and inflammatory bowel diseases. However, there are no single species can be proven to play a key factor in pediatric obesity and NAFLD at present. Various probiotics may confer benefit to these gut microbiota-related pediatric diseases. The clinical application is still limited. This review article aimed to elucidate evidently the relationship between gut microbiota and pediatric obesity/NAFLD and to discuss the potential probiotics use in pediatric obesity and NAFLD.

頁(從 - 到)S55-S61
期刊Journal of the Formosan Medical Association
出版狀態Published - 2019 3月

All Science Journal Classification (ASJC) codes

  • 醫藥 (全部)


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