Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan.

T. T. Chang, C. Y. Lin, N. H. Chow, P. I. Hsu, C. C. Yang, X. Z. Lin, J. S. Shin, D. S. Chen

研究成果: Article

9 引文 (Scopus)

摘要

The prevalence of the anti-hepatitis C virus (anti-HCV) antibody and hepatitis B surface antigen (HBsAg) among 123 alcoholic patients with liver disease from our hospital and 44 alcoholic subjects from the local community was evaluated. By radio-immunoassay HBsAg was detected in 30.1% of alcoholic patients with liver disease, compared with 11.4% of alcoholic subjects from the local community (p < 0.05). The prevalence of HBsAg was 40.7% (11/27) in patients with cirrhosis and hepatocellular carcinoma (HCC), 31.5% (17/54) in patients with cirrhosis only, and 29.4% (5/17) in patients with other liver diseases. By enzyme-linked immunosorbent assay, anti-HCV antibody was detected in 30.9% of alcoholic patients with liver disease, compared with 2.3% of alcoholic subjects from the local community (p < 0.0005). The prevalence of anti-HCV antibody was 44.4% in alcoholic patients with cirrhosis and HCC, 29.6% in alcoholic patients with cirrhosis only, and 17.6% in alcoholic patients with other liver diseases. As the degree of liver damage advanced, the prevalence of either HBsAg or anti-HCV antibody, or both, being detected in these alcoholic patients increased significantly (p < 0.05). The serum ALT level was higher among alcoholic patients who had either HBsAg or anti-HCV antibody than those having neither (151 +/- 204 vs 62 +/- 47 IU/L; p < 0.005). All three alcoholic patients with chronic hepatitis had positive HBsAg or anti-HCV antibody. Histologic findings, except cells within sinusoids, were comparable between the alcoholic patients with or without superimposed hepatitis viruses.(ABSTRACT TRUNCATED AT 250 WORDS)

原文English
頁（從 - 到）128-133
頁數6
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
卷93
發行號2
出版狀態Published - 1994 二月

指紋

Virus Diseases
Alcoholics
Hepatitis B
Taiwan
Hepacivirus
Liver Diseases
Hepatitis C Antibodies
Hepatitis B Surface Antigens
Fibrosis
Hepatocellular Carcinoma
Hepatitis Viruses
Chronic Hepatitis
Radio
Immunoassay
Enzyme-Linked Immunosorbent Assay

All Science Journal Classification (ASJC) codes

  • Medicine(all)

引用此文

Chang, T. T. ; Lin, C. Y. ; Chow, N. H. ; Hsu, P. I. ; Yang, C. C. ; Lin, X. Z. ; Shin, J. S. ; Chen, D. S. / Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan. 於: Journal of the Formosan Medical Association = Taiwan yi zhi. 1994 ; 卷 93, 編號 2. 頁 128-133.
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title = "Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan.",
abstract = "The prevalence of the anti-hepatitis C virus (anti-HCV) antibody and hepatitis B surface antigen (HBsAg) among 123 alcoholic patients with liver disease from our hospital and 44 alcoholic subjects from the local community was evaluated. By radio-immunoassay HBsAg was detected in 30.1{\%} of alcoholic patients with liver disease, compared with 11.4{\%} of alcoholic subjects from the local community (p < 0.05). The prevalence of HBsAg was 40.7{\%} (11/27) in patients with cirrhosis and hepatocellular carcinoma (HCC), 31.5{\%} (17/54) in patients with cirrhosis only, and 29.4{\%} (5/17) in patients with other liver diseases. By enzyme-linked immunosorbent assay, anti-HCV antibody was detected in 30.9{\%} of alcoholic patients with liver disease, compared with 2.3{\%} of alcoholic subjects from the local community (p < 0.0005). The prevalence of anti-HCV antibody was 44.4{\%} in alcoholic patients with cirrhosis and HCC, 29.6{\%} in alcoholic patients with cirrhosis only, and 17.6{\%} in alcoholic patients with other liver diseases. As the degree of liver damage advanced, the prevalence of either HBsAg or anti-HCV antibody, or both, being detected in these alcoholic patients increased significantly (p < 0.05). The serum ALT level was higher among alcoholic patients who had either HBsAg or anti-HCV antibody than those having neither (151 +/- 204 vs 62 +/- 47 IU/L; p < 0.005). All three alcoholic patients with chronic hepatitis had positive HBsAg or anti-HCV antibody. Histologic findings, except cells within sinusoids, were comparable between the alcoholic patients with or without superimposed hepatitis viruses.(ABSTRACT TRUNCATED AT 250 WORDS)",
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Chang, TT, Lin, CY, Chow, NH, Hsu, PI, Yang, CC, Lin, XZ, Shin, JS & Chen, DS 1994, 'Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan.', Journal of the Formosan Medical Association = Taiwan yi zhi, 卷 93, 編號 2, 頁 128-133.

Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan. / Chang, T. T.; Lin, C. Y.; Chow, N. H.; Hsu, P. I.; Yang, C. C.; Lin, X. Z.; Shin, J. S.; Chen, D. S.

於: Journal of the Formosan Medical Association = Taiwan yi zhi, 卷 93, 編號 2, 02.1994, p. 128-133.

研究成果: Article

TY - JOUR

T1 - Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan.

AU - Chang, T. T.

AU - Lin, C. Y.

AU - Chow, N. H.

AU - Hsu, P. I.

AU - Yang, C. C.

AU - Lin, X. Z.

AU - Shin, J. S.

AU - Chen, D. S.

PY - 1994/2

Y1 - 1994/2

N2 - The prevalence of the anti-hepatitis C virus (anti-HCV) antibody and hepatitis B surface antigen (HBsAg) among 123 alcoholic patients with liver disease from our hospital and 44 alcoholic subjects from the local community was evaluated. By radio-immunoassay HBsAg was detected in 30.1% of alcoholic patients with liver disease, compared with 11.4% of alcoholic subjects from the local community (p < 0.05). The prevalence of HBsAg was 40.7% (11/27) in patients with cirrhosis and hepatocellular carcinoma (HCC), 31.5% (17/54) in patients with cirrhosis only, and 29.4% (5/17) in patients with other liver diseases. By enzyme-linked immunosorbent assay, anti-HCV antibody was detected in 30.9% of alcoholic patients with liver disease, compared with 2.3% of alcoholic subjects from the local community (p < 0.0005). The prevalence of anti-HCV antibody was 44.4% in alcoholic patients with cirrhosis and HCC, 29.6% in alcoholic patients with cirrhosis only, and 17.6% in alcoholic patients with other liver diseases. As the degree of liver damage advanced, the prevalence of either HBsAg or anti-HCV antibody, or both, being detected in these alcoholic patients increased significantly (p < 0.05). The serum ALT level was higher among alcoholic patients who had either HBsAg or anti-HCV antibody than those having neither (151 +/- 204 vs 62 +/- 47 IU/L; p < 0.005). All three alcoholic patients with chronic hepatitis had positive HBsAg or anti-HCV antibody. Histologic findings, except cells within sinusoids, were comparable between the alcoholic patients with or without superimposed hepatitis viruses.(ABSTRACT TRUNCATED AT 250 WORDS)

AB - The prevalence of the anti-hepatitis C virus (anti-HCV) antibody and hepatitis B surface antigen (HBsAg) among 123 alcoholic patients with liver disease from our hospital and 44 alcoholic subjects from the local community was evaluated. By radio-immunoassay HBsAg was detected in 30.1% of alcoholic patients with liver disease, compared with 11.4% of alcoholic subjects from the local community (p < 0.05). The prevalence of HBsAg was 40.7% (11/27) in patients with cirrhosis and hepatocellular carcinoma (HCC), 31.5% (17/54) in patients with cirrhosis only, and 29.4% (5/17) in patients with other liver diseases. By enzyme-linked immunosorbent assay, anti-HCV antibody was detected in 30.9% of alcoholic patients with liver disease, compared with 2.3% of alcoholic subjects from the local community (p < 0.0005). The prevalence of anti-HCV antibody was 44.4% in alcoholic patients with cirrhosis and HCC, 29.6% in alcoholic patients with cirrhosis only, and 17.6% in alcoholic patients with other liver diseases. As the degree of liver damage advanced, the prevalence of either HBsAg or anti-HCV antibody, or both, being detected in these alcoholic patients increased significantly (p < 0.05). The serum ALT level was higher among alcoholic patients who had either HBsAg or anti-HCV antibody than those having neither (151 +/- 204 vs 62 +/- 47 IU/L; p < 0.005). All three alcoholic patients with chronic hepatitis had positive HBsAg or anti-HCV antibody. Histologic findings, except cells within sinusoids, were comparable between the alcoholic patients with or without superimposed hepatitis viruses.(ABSTRACT TRUNCATED AT 250 WORDS)

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JO - Journal of the Formosan Medical Association

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Chang TT, Lin CY, Chow NH, Hsu PI, Yang CC, Lin XZ 等. Hepatitis B and hepatitis C virus infection among chronic alcoholic patients with liver disease in Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi. 1994 2月;93(2):128-133.

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