High case-fatality rate of adults with dengue hemorrhagic fever during an outbreak in non-endemic Taiwan: Risk factors for dengue-infected elders

Ching-Chuan Liu, Kao Jean Huang, Mei-Chih Huang, J. J. Lin, Shih-Min Wang, Jen Jou Liu, Jih Jin Tsai, Jyh Hsiung Huang, Yee-Shin Lin, Hsiao-Sheng Liu, Trai-Ming Yeh, Huan Yao Lei

研究成果: Article

13 引文 (Scopus)

摘要

In 2002, a dengue outbreak occurred in Taiwan with 5336 confirmed cases, 242 DHF and 21 death, the case fatality rate reached 8.7% (21/242). The demographic data of these age-specific dengue patients showed that dengue virus infection caused symptom primarily occurred in adults. A comparative analysis of clinical and laboratory data for DF, DHF/DSS and fatal DSS found that high fatality from dengue infection was associated with the following patient conditions: (1) age above 55 years, (2) underlying diseases with hypertension, chronic renal insufficiency, or diabetes, (3) abnormal thrombocytopenia, APTT and PT prolongation, low hematocrit (<30%) and leukocytosis, (4) abnormal elevation of AST, ALT and BUN. In a non-endemic area like Taiwan, dengue should be considered as an adult infectious disease and the dengue-infected elders will have higher morbidity or mortality.

原文English
頁(從 - 到)10-17
頁數8
期刊American Journal of Infectious Diseases
4
發行號1
DOIs
出版狀態Published - 2008 一月 1

指紋

Severe Dengue
Dengue
Taiwan
Disease Outbreaks
Mortality
Dengue Virus
Blood Urea Nitrogen
Leukocytosis
Virus Diseases
Chronic Renal Insufficiency
Hematocrit
Communicable Diseases
Demography
Hypertension
Morbidity
Infection

All Science Journal Classification (ASJC) codes

  • Infectious Diseases

引用此文

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title = "High case-fatality rate of adults with dengue hemorrhagic fever during an outbreak in non-endemic Taiwan: Risk factors for dengue-infected elders",
abstract = "In 2002, a dengue outbreak occurred in Taiwan with 5336 confirmed cases, 242 DHF and 21 death, the case fatality rate reached 8.7{\%} (21/242). The demographic data of these age-specific dengue patients showed that dengue virus infection caused symptom primarily occurred in adults. A comparative analysis of clinical and laboratory data for DF, DHF/DSS and fatal DSS found that high fatality from dengue infection was associated with the following patient conditions: (1) age above 55 years, (2) underlying diseases with hypertension, chronic renal insufficiency, or diabetes, (3) abnormal thrombocytopenia, APTT and PT prolongation, low hematocrit (<30{\%}) and leukocytosis, (4) abnormal elevation of AST, ALT and BUN. In a non-endemic area like Taiwan, dengue should be considered as an adult infectious disease and the dengue-infected elders will have higher morbidity or mortality.",
author = "Ching-Chuan Liu and Huang, {Kao Jean} and Mei-Chih Huang and Lin, {J. J.} and Shih-Min Wang and Liu, {Jen Jou} and Tsai, {Jih Jin} and Huang, {Jyh Hsiung} and Yee-Shin Lin and Hsiao-Sheng Liu and Trai-Ming Yeh and Lei, {Huan Yao}",
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High case-fatality rate of adults with dengue hemorrhagic fever during an outbreak in non-endemic Taiwan : Risk factors for dengue-infected elders. / Liu, Ching-Chuan; Huang, Kao Jean; Huang, Mei-Chih; Lin, J. J.; Wang, Shih-Min; Liu, Jen Jou; Tsai, Jih Jin; Huang, Jyh Hsiung; Lin, Yee-Shin; Liu, Hsiao-Sheng; Yeh, Trai-Ming; Lei, Huan Yao.

於: American Journal of Infectious Diseases, 卷 4, 編號 1, 01.01.2008, p. 10-17.

研究成果: Article

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AU - Liu, Ching-Chuan

AU - Huang, Kao Jean

AU - Huang, Mei-Chih

AU - Lin, J. J.

AU - Wang, Shih-Min

AU - Liu, Jen Jou

AU - Tsai, Jih Jin

AU - Huang, Jyh Hsiung

AU - Lin, Yee-Shin

AU - Liu, Hsiao-Sheng

AU - Yeh, Trai-Ming

AU - Lei, Huan Yao

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