@article{160ee5e9fd8947508dff8b69ad76c388,
title = "High-speed photoacoustic microscopy of mouse cortical microhemodynamics",
abstract = "We applied high-speed photoacoustic microscopy (PAM) for both cortical microenvironment studies and dynamic brain studies, with micrometer-level optical resolution and a millisecond-level cross-sectional imaging speed over a millimeter-level field of view. We monitored blood flow redistribution in mini-stroke mouse models and cerebral autoregulation induced by a vasoactive agent. Our results collectively suggest that high-speed PAM is a promising tool for understanding dynamic neurophysiological phenomena, complementing conventional imaging modalities. (Figure presented.).",
author = "Li Lin and Junjie Yao and Ruiying Zhang and Chen, {Chun Cheng} and Huang, {Chih Hsien} and Yang Li and Lidai Wang and William Chapman and Jun Zou and Wang, {Lihong V.}",
note = "Funding Information: The authors appreciate Prof. James Ballard's close reading of the manuscript. We also thank Peng Hu for image processing. This work was sponsored by NIH grants R01 CA186567 (NIH Director's Transformative Research Award), and R01 CA159959 (for L. V. Wang), and NSF grant IDBR-1255921 (for J. Zou). L. V. Wang has a financial interest in Microphotoacoustics, Inc., which, however, did not support this work. Publisher Copyright: {\textcopyright} 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2017",
month = jun,
doi = "10.1002/jbio.201600236",
language = "English",
volume = "10",
pages = "792--798",
journal = "Journal of Biophotonics",
issn = "1864-063X",
publisher = "Wiley-VCH Verlag",
number = "6",
}