High-speed three-dimensional characterization of fluid flows induced by micro-objects in deep microchannels

Chia Yuan Chen, Kerem Pekkan

研究成果: Article同行評審

4 引文 斯高帕斯(Scopus)

摘要

Bio-inspired studies of micro-objects in microfluidics demand quantitative microflow visualization tools to evaluate their three-dimensional (3D) fluid dynamic performance. Experimental fluid dynamic measurements of bio-hybrid systems are employed when non-traditional small-scales, magnetohydrodynamic coupling and nonlinear material properties are involved. In this study a stereoscopic micro- Particle Image Velocimetry (μPIV) system was developed to characterize instantaneous flow fields induced by (1) a micro-robot (280×200×150 μm3) and (2) self-assembled magnetically actuated artificial cilia (∼50 μm in diameter and 500 μm in depth). A custom built micro jet flow microchannel was tested to provide the quantitative evidence of measurement accuracy with 14% error compared to theoretical solutions in the out-of-plane velocity component. Followed by these verification experiments, instantaneous in-plane spinning motion was analyzed in conjunction with translational movement and out-of-plane rotational movements of the micro-robot to obtain the induced 2D-3C (two-dimension, three-component) fluid velocity data. The second test case investigated the microscale vortical flow structures that were generated by self-assembled magnetically driven artificial cilia. The strength of this 3D micro vortex structure was computed based on the 3D flow measurements. In combination with the asymmetric cyclic motion of the magnetically actuated artificial cilia, it is expected that these structures can generate transverse flow efficiently in 3D, and thus provide a potential alternative for mixing in low Reynolds number flows, analogous to a micromixer. The acquired 3D microflow field, along with the validation tests, further extends the capability of using stereoscopic μPIV technique to evaluate the performance of noninvasive microflow manipulators.

原文English
頁(從 - 到)95-103
頁數9
期刊Biochip Journal
7
發行號2
DOIs
出版狀態Published - 2013 六月

All Science Journal Classification (ASJC) codes

  • 生物技術
  • 生物工程
  • 生物醫學工程
  • 電氣與電子工程

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