Home-time as a surrogate measure for functional outcome after stroke: A validation study

Sheng Feng Sung, Chien Chou Su, Cheng Yang Hsieh, Ching Lan Cheng, Chih Hung Chen, Huey Juan Lin, Yu Wei Chen, Yea Huei Kao Yang

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)

摘要

Purpose: Home-time has been found to correlate well with modified Rankin Scale (mRS) scores in patients with stroke. This study aimed to determine its correlations in patients with different types of stroke at various time points after stroke in a non-Western population. Methods: This study used linked data from multi-center stroke registry databases and a nationwide claims database of health insurance. Functional outcomes as measured with the modified Rankin Scale were obtained from the registry databases and home-time was derived from the claims database. Spearman correlation coefficients were used to assess the correlation between home-time and mRS scores. The area under the receiver operating characteristic curve (AUC) was used to evaluate the performance of home-time in predicting good functional outcome. Results: This study included 7959 patients hospitalized for stroke or transient ischemic attack (TIA), for whom mRS scores were available in 6809, 6694, and 4330 patients at 90, 180, and 365 days, respectively. Home-time was highly correlated with mRS scores at the three time-points in patients with ischemic (Spearman’s rho −0.69 to −0.83) or hemorrhagic (Spearman’s rho −0.86 to −0.88) stroke, but the correlation was only weak to moderate in those with TIA (Spearman’s rho −0.32 to −0.58). Home-time predicted good functional outcome with excellent discrimination in patients with ischemic (AUCs >0.8) or hemorrhagic (AUCs >0.9) stroke but less so in those with TIA (AUCs >0.7). Conclusion: Home-time was highly correlated with mRS scores and showed excellent discrimination in predicting good functional outcome in patients with ischemic or hemorrhagic stroke. Home-time could serve as a valid surrogate measure for functional outcome after stroke.

原文English
頁(從 - 到)617-624
頁數8
期刊Clinical Epidemiology
12
DOIs
出版狀態Published - 2020

All Science Journal Classification (ASJC) codes

  • 流行病學

指紋

深入研究「Home-time as a surrogate measure for functional outcome after stroke: A validation study」主題。共同形成了獨特的指紋。

引用此