Impact of liver cirrhosis on mortality in patients with community-acquired bacteremia

Shey Ying Chen, Chu Lin Tsai, Chien Hao Lin, Chien Chang Lee, Wen Chu Chiang, Jiun Ling Wang, Matthew Huei Ming Ma, Shyr Chyr Chen, Wen Jone Chen, Shan Chwen Chang

研究成果: Article

25 引文 斯高帕斯(Scopus)

摘要

Few studies have analyzed the impact of liver cirrhosis, a clinically significant comorbid medical condition, on the mortality of patients with community-acquired bacteremia. We conducted an observational study of 839 consecutive community-acquired bacteremia patients who were hospitalized through the emergency department (ED). We compared the 30-day mortality of bacteremia patients with and without liver cirrhosis using Cox proportional hazards regression. The probability of survival at day 30 was significantly different for the cirrhotic and noncirrhotic groups (53% versus 82%, respectively; P < 0.001 by the log-rank test). Multivariate analysis indicated that liver cirrhosis was associated with an increased risk of short-term mortality (hazard ratio, 2.0; 95% confidence interval, 1.1-3.5), as well as age, higher comorbidity index, and markers obtained from clinical presentation at ED. In conclusion, in addition to the effects from other prognostic factors, liver cirrhosis has a significant impact on the mortality of patients with community-acquired bacteremia.

原文English
頁(從 - 到)124-130
頁數7
期刊Diagnostic Microbiology and Infectious Disease
64
發行號2
DOIs
出版狀態Published - 2009 六月 1

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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    Chen, S. Y., Tsai, C. L., Lin, C. H., Lee, C. C., Chiang, W. C., Wang, J. L., Ma, M. H. M., Chen, S. C., Chen, W. J., & Chang, S. C. (2009). Impact of liver cirrhosis on mortality in patients with community-acquired bacteremia. Diagnostic Microbiology and Infectious Disease, 64(2), 124-130. https://doi.org/10.1016/j.diagmicrobio.2009.01.008