In situ encapsulation of antibody on TiO2 nanowire immunosensor via electro-polymerization of polypyrrole propylic acid

Chi Chang Lin, Yung Ming Chu, Hsien Chang Chang

研究成果: Article同行評審

19 引文 斯高帕斯(Scopus)

摘要

A conductance-based immunosensor was constructed based on an antibody/conducting polymer/TiO2 nanowire film. TiO2 nanowires (NWs) were made by the hydrothermal synthesis method and directly spin-coated on a gold microelectrode patterned surface. Conducting polymer polypyrrole propylic acid (PPa) and antibody composite films were electrochemically polymerized on patterned NWs using pyrrole propylic acid (Pa) and anti-rabbit IgG (1 Ab) mixture solutions. The surface properties in the designed immunosensor during the preparation processes of NWs, PPa (PPa/TiO 2 NWs), anti-rabbit IgG (PPa-1 Ab/TiO2 NWs immunosensor), and the measurement of rabbit IgG (2 Ab/PPa-1 Ab/TiO2 NWs immunosensor) were recorded and expressed by the changes in current-voltage (I-V). The devices designed in this study can detect 2 Ab within a linear range of 11.2 μg/mL to 112 μg/mL, and the detection sensitivity and R-square are -0.64A/(g/mL) and 0.896, respectively.

原文English
頁(從 - 到)533-539
頁數7
期刊Sensors and Actuators, B: Chemical
187
DOIs
出版狀態Published - 2013

All Science Journal Classification (ASJC) codes

  • 電子、光磁材料
  • 儀器
  • 凝聚態物理學
  • 表面、塗料和薄膜
  • 金屬和合金
  • 電氣與電子工程
  • 材料化學

指紋

深入研究「In situ encapsulation of antibody on TiO2 nanowire immunosensor via electro-polymerization of polypyrrole propylic acid」主題。共同形成了獨特的指紋。

引用此