TY - JOUR
T1 - Induced pluripotent stem cell (iPSC) line MLi-004A derived from a patient with recessive dystrophic epidermolysis bullosa (RDEB)
AU - Ropret, Sandra
AU - Jeriha, Jakob
AU - Sorčan, Tjaša
AU - Rogar, Marija
AU - Zemljič Jokhadar, Špela
AU - McGrath, John A.
AU - Ilic, Dusko
AU - Liovic, Mirjana
N1 - Publisher Copyright:
© 2021 The Authors
PY - 2021/8
Y1 - 2021/8
N2 - We have generated MLi004-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a female patient with recessive dystrophic epidermolysis bullosa (RDEB). This iPSC line may be used as a model system for studies on skin integrity, the extracellular matrix and skin barrier function. The characterization of the MLi004-A cell line consisted of molecular karyotyping, next-generation sequencing of the COL7A1 alleles, pluripotency and differentiation potentials testing by immunofluorescence of associated markers in vitro. The MLi-004A line has been also tested for ability to differentiate into fibroblasts.
AB - We have generated MLi004-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a female patient with recessive dystrophic epidermolysis bullosa (RDEB). This iPSC line may be used as a model system for studies on skin integrity, the extracellular matrix and skin barrier function. The characterization of the MLi004-A cell line consisted of molecular karyotyping, next-generation sequencing of the COL7A1 alleles, pluripotency and differentiation potentials testing by immunofluorescence of associated markers in vitro. The MLi-004A line has been also tested for ability to differentiate into fibroblasts.
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U2 - 10.1016/j.scr.2021.102463
DO - 10.1016/j.scr.2021.102463
M3 - Article
C2 - 34284275
AN - SCOPUS:85110391206
SN - 1873-5061
VL - 55
JO - Stem Cell Research
JF - Stem Cell Research
M1 - 102463
ER -