TY - GEN
T1 - Influence of stimulus waveforms of high-frequency electrical current on nerve conduction block
AU - Peng, Chih Wei
AU - Chen, Shih Ching
AU - Fan, Wen Jia
AU - Lai, Chien Hung
AU - Chen, Jia-Jin
PY - 2009/10/27
Y1 - 2009/10/27
N2 - The aim of this study was to determine the effect of monophasic, biphasic symmetric, and biphasic asymmetric balanced rectangular stimulus waveforms utilized in high-frequency electrical conduction block of nerve fibers. From the animal studies, we found that blocking stimulus with monophasic or biphasic asymmetric waveform at varied blocking current amplitudes showed better blocking effect, which can manipulate the maximal available torque up to 99%. However, the blocking effect of biphasic symmetric waveform only had up to 73%. In muscle fatigue tests, the reactive torque resulted from biphasic symmetric stimulus exhibited a rapid decreasing fatigue curve when compared to the curves induced by other tested waveforms. All those results demonstrated that the stimulus waveform was an important factor affected the nerve blocking efficiency and muscle fatigue pattern.
AB - The aim of this study was to determine the effect of monophasic, biphasic symmetric, and biphasic asymmetric balanced rectangular stimulus waveforms utilized in high-frequency electrical conduction block of nerve fibers. From the animal studies, we found that blocking stimulus with monophasic or biphasic asymmetric waveform at varied blocking current amplitudes showed better blocking effect, which can manipulate the maximal available torque up to 99%. However, the blocking effect of biphasic symmetric waveform only had up to 73%. In muscle fatigue tests, the reactive torque resulted from biphasic symmetric stimulus exhibited a rapid decreasing fatigue curve when compared to the curves induced by other tested waveforms. All those results demonstrated that the stimulus waveform was an important factor affected the nerve blocking efficiency and muscle fatigue pattern.
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U2 - 10.1109/NER.2009.5109237
DO - 10.1109/NER.2009.5109237
M3 - Conference contribution
AN - SCOPUS:70350234773
SN - 9781424420735
T3 - 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09
SP - 72
EP - 75
BT - 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09
T2 - 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09
Y2 - 29 April 2009 through 2 May 2009
ER -