Integrated microfluidic system for HIV detection

Jung Hao Wang, Chih Hung Wang, Wei Shuo Ling, Lie Jheng, Shainn-Wei Wang, Gwo Bin Lee

研究成果: Conference contribution

1 引文 斯高帕斯(Scopus)

摘要

This study presents a new microfluidic system for molecular diagnosis of human immunodeficiency virus (HIV) infection. In this study, magnetic beads conjugated with nucleotide probes specific to HIV were used to perform purification and enrichment of target DNA. Then an on-chip PCR module was used to perform amplification of four detection genes associated with HIV infection. Finally, an optical module was used to detect the amplified PCR products. Experimental results demonstrated that multiple HIV detection fragments could be amplified successfully and detected on-line using the developed microfluidic system in the HIV-infected cell line within 95 min, which is much faster than the existing methods.

原文English
主出版物標題2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
頁面961-964
頁數4
DOIs
出版狀態Published - 2012 五月 7
事件2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 - Paris, France
持續時間: 2012 一月 292012 二月 2

出版系列

名字Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN(列印)1084-6999

Other

Other2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
國家France
城市Paris
期間12-01-2912-02-02

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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  • 引用此

    Wang, J. H., Wang, C. H., Ling, W. S., Jheng, L., Wang, S-W., & Lee, G. B. (2012). Integrated microfluidic system for HIV detection. 於 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 (頁 961-964). [6170346] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2012.6170346