Classroom is a professional field of teaching and learning. After going to classrooms, teachers have to face curriculums, each student, and other dimensions and needs. Besides careful management, adjustment of teaching strategies should be considered according to individual difference, and this can achieve win–win relationship between teachers and students, and create a friendly learning environment. Thus, satisfying learners’ different needs for learning is an important issue in the education domain. Owing to the advent of e-book, it provides educators a new way to conveniently assess every student’s learning status in diverse dimensions. For example, one potential advantage is the greater flexibility and accessibility of e-books over paper books, and the characteristics of e-books could provide authentic contexts and activities. Therefore, e-books have the potential capacity to achieve authentic learning instead of traditional textbooks. With the experiences in the development of e-books and educational technologies, we have seen an emerging trend in the application of e-books to authentic learning. Therefore, this chapter aims to investigate the suitability of different kinds of e-books for the educational environments, and the potential benefits of integrating e-book in authentic learning. It is hoped to suggest readers a further research blueprint for this topic.