Intermediate filaments in motion: Observations of intermediate filaments in cells using green fluorescent protein-vimentin

Jayme L. Martys, Chung Liang Ho, Ronald K.H. Liem, Gregg G. Gundersen

研究成果: Review article同行評審

61 引文 斯高帕斯(Scopus)

摘要

In the movies presented in this essay we have demonstrated that IFs are dynamic in nature. Movements of IFs include both extension and retraction and are dependent on the presence of intact MTs. Furthermore, we have characterized a possible intermediate of IF turnover, IF fragments. These fragments are also dynamic and can be visualized moving at the leading edge of cells migrating into a wound edge. Interestingly, the movement of these fragments is also dependent on intact MTs, suggesting that MTs may play a role in turnover of IFs.

原文English
頁(從 - 到)1289-1295
頁數7
期刊Molecular Biology of the Cell
10
發行號5
DOIs
出版狀態Published - 1999 五月

All Science Journal Classification (ASJC) codes

  • 分子生物學
  • 細胞生物學

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