Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

Shiow Chyn Huang; Ping Chung Kuo; Hsin Yi Hung; Tai Long Pan; Fu An Chen; Tian Shung Wu

doi:10.3390/ijms17050681

Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

Shiow Chyn Huang, Ping Chung Kuo, Hsin Yi Hung, Tai Long Pan, Fu An Chen, Tian Shung Wu

研究成果: Letter › 同行評審

8 引文斯高帕斯（Scopus）

摘要

Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

原文	English
文章編號	681
期刊	International journal of molecular sciences
卷	17
發行號	5
DOIs	https://doi.org/10.3390/ijms17050681
出版狀態	Published - 2016 5月 6

All Science Journal Classification (ASJC) codes

催化
分子生物學
光譜
電腦科學應用
物理與理論化學
有機化學
無機化學

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10.3390/ijms17050681

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abstract = "Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.",

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AU - Huang, Shiow Chyn

AU - Kuo, Ping Chung

AU - Hung, Hsin Yi

AU - Pan, Tai Long

AU - Chen, Fu An

AU - Wu, Tian Shung

PY - 2016/5/6

Y1 - 2016/5/6

N2 - Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

AB - Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

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M3 - Letter

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JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1661-6596

IS - 5

M1 - 681

ER -

Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

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