Is there different risk of cancer among end-stage renal disease patients undergoing hemodialysis and peritoneal dialysis?

Yi Che Lee, Shih Yuan Hung, Hao Kuang Wang, Chi Wei Lin, Hsi Hao Wang, Min Yu Chang, Junne Ming Sung, Yuan Yow Chiou, Sheng Hsiang Lin

研究成果: Article同行評審

24 引文 斯高帕斯(Scopus)

摘要

Cancer is a global issue in recent decade. Despite this alarming increase in the incidence of cancer, to date, whether the risk of developing cancer differs among peritoneal dialysis (PD) and hemodialysis (HD) patients is still uncertain. In this retrospective cohort study, data were obtained from the National Health Insurance Research Database of Taiwan, which provides coverage to almost 99% of the nation's population. After matching, a total of 4491 (or 3369) incident PD patients and 8982 (or 6738) incident HD patients between 2000 and 2009 were enrolled from the database. In addition, 22,455 (or 16,845) nondialysis patients were selected as a control group. The patients were monitored for the occurrence of cancer until 2010, and their data were analyzed using several different models. In general, the results showed that the risks of hepatocellular, kidney, bladder, extra kidney/bladder urinary tract, and thyroid cancers were higher in dialysis patients. We also compared the risk of cancer between two dialysis groups by using the HD patients as the reference group. The result showed that there is no significant different for each cancer risk between two dialysis groups. In conclusion, dialysis patients had a higher risk of certain types of cancer than those in the nonuremia group. However, there was no significant difference in the cancer risk between the two dialysis groups when compared directly.

原文English
頁(從 - 到)485-498
頁數14
期刊Cancer medicine
7
發行號2
DOIs
出版狀態Published - 2018 2月

All Science Journal Classification (ASJC) codes

  • 腫瘤科
  • 放射學、核子醫學和影像學
  • 癌症研究

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