Isolation and characterization of a Vibrio vulnificus mutant deficient in both extracellular metalloprotease and cytolysin

J. J. Fan, C. P. Shao, Y. C. Ho, C. K. Yu, L. I. Hor

研究成果: Article同行評審

72 引文 斯高帕斯(Scopus)

摘要

We isolated a Vibrio vulnificus mutant that was deficient in both metalloprotease and cytolysin by allelic exchange. The virulence of this mutant in mice and its cytotoxicity for HEp-2 cells were comparable to those of the wild-type strain, indicating that neither factor was essential for these properties. The cytolysin, but not the protease, seemed to be important for causing damage in the alimentary tract of the mice.

原文English
頁(從 - 到)5943-5948
頁數6
期刊Infection and Immunity
69
發行號9
DOIs
出版狀態Published - 2001

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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