@article{6ef8e4d275c44098aac7cda2c3b9d56c,
title = "Labdanecaryophyllic acid, a novel cytotoxic C35 terpenoid from Calocedrus macrolepis var. formosana",
abstract = "Chemical investigation of the bark of Calocedrus macrolepis var. formosana, an endemic tree in Taiwan, has led to the isolation of a novel terpenoid 1. Compound 1 with a rare C35 skeleton constructed by a diterpene and a sesquiterpene moieties. Its structure was elucidated by spectroscopic interpretations. The anti-proliferation activity of 1 against human oral epidermoid carcinoma KB cells was evaluated, and the IC50 value was determined to be 9.2 ± 0.4 μM.",
author = "Hsien, {Chin Lin} and Tseng, {Mei Hwei} and Pan, {Ryh Nan} and Chang, {Jang Yang} and Kuo, {Ching Chuan} and Lee, {Tzong Huei} and Kuo, {Yueh Hsiung}",
note = "Funding Information: This study was supported by China Medical University ( CMU98-CT-2 ), Taiwan Department of Health Clinical Trial and Research Center of Excellence ( DOH99-TD-B-111-004 ), and Cancer Research Center of Excellence ( DOH99-TD-C-111-005 ). Copyright: Copyright 2011 Elsevier B.V., All rights reserved.",
year = "2011",
month = jan,
day = "26",
doi = "10.1016/j.tetlet.2010.11.101",
language = "English",
volume = "52",
pages = "515--517",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "4",
}