Left ventricular systolic strain in chronic kidney disease and hemodialysis patients

Yen Wen Liu, Chi Ting Su, Yao Yi Huang, Chun Shin Yang, Jenq Wen Huang, Mao Ting Yang, Jyh Hong Chen, Wei Chuan Tsai

研究成果: Article同行評審

67 引文 斯高帕斯(Scopus)

摘要

Background: The impact of chronic kidney disease (CKD) and hemodialysis on heart function is not fully understood. We aimed to investigate the influence of different stages of CKD and maintenance hemodialysis on heart function. Methods: One hundred fifty-three patients were categorized into 3 subgroups [56 without CKD as controls; 37 with moderate-advanced CKD, stages 3, 4 or 5, and 60 with end-stage renal disease (ESRD) undergoing maintenance hemodialysis]. Left ventricular (LV) function was assessed by conventional echocardiography and 2-dimensional speckle-tracking echocardiography with strain analysis (2D strain analysis). Results: There was no significant difference of gender, age and LV ejection fraction among groups. Compared with controls, global peak systolic longitudinal strain (GSl), circumferential strain and strain rate were decreased in the CKD group. Along with the decline of renal function, GSl deteriorated. Moreover, compared with moderate-advanced CKD patients, GSl, circumferential strain and strain rate were better in ESRD group receiving maintenance hemodialysis. Conclusions: Worsening renal function was associated with a reduction of systolic function, and could be quantified by 2D strain analysis. The hemodialysis patients have better LV systolic function than the moderate-advanced CKD patients.

原文English
頁(從 - 到)84-90
頁數7
期刊American Journal of Nephrology
33
發行號1
DOIs
出版狀態Published - 2011 一月

All Science Journal Classification (ASJC) codes

  • 腎臟病學

指紋

深入研究「Left ventricular systolic strain in chronic kidney disease and hemodialysis patients」主題。共同形成了獨特的指紋。

引用此