Legionnaires’ disease at a medical center in southern Taiwan

Tzu Lun Hung, Ming Chi Li, Li Rong Wang, Ching Chuan Liu, Chia Wen Li, Po Lin Chen, Ling Shan Syue, Nan Yao Lee, Wen Chien Ko

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)


Background/purpose: Legionella pneumophila had been recognized as a pathogen for both healthcare-associated and community-acquired pneumonia. We aimed to evaluate clinical features and outcomes of patients with Legionnaires’ disease at a tertiary medical center in southern Taiwan. Methods: From January 2005 to December 2013, a retrospective study of adult cases of Legionnaires’ disease was conducted in a 1200-bed tertiary hospital. Their medical records were reviewed for further evaluation and analysis. Results: A total of 61 cases of Legionnaires’ disease were identified during the study period. Their mean age was 61.1 years, with male predominance (43, 70.5%). Among them, 30 (49.2%) had healthcare-associated pneumonia (HCAP), 20 (32.8%) had community-acquired pneumonia, and notably 11 (18.0%) were caregivers. Patients with healthcare-associated pneumonia tend to have higher Charlson comorbidity scores than those with community-acquired pneumonia (3.6 ± 2.4 vs. 1.9 ± 1.9, p = 0.008) and caregivers (0.5 ± 0.5, p < 0.001). Six patients died, resulting in an in-hospital mortality rate of 9.8%. Underlying cancer (66.7% vs. 20.0%, p = 0.028) and a higher Charlson comorbidity score (4.7 ± 2.6 vs. 2.2 ± 2.2, p = 0.013) were related to a fatal outcome. Conclusion: L. pneumophila remains an important pathogen for pneumonia acquired from the community or associated with healthcare facility. Healthy caregivers may potentially be at risk for Legionella infection in certain clinical settings.

頁(從 - 到)352-358
期刊Journal of Microbiology, Immunology and Infection
出版狀態Published - 2018 6月

All Science Journal Classification (ASJC) codes

  • 免疫學和過敏
  • 一般免疫學和微生物學
  • 微生物學(醫學)
  • 傳染性疾病


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