Investigation of the root of Cinnamomum philippinense resulted in the isolation of a new lignan, cinnamophilin, together with three known compounds, meso-dihydroguaiaretic acid, (+)-guaiacin and vallinic acid. Their structures were elucidated by spectral analysis. Cinnamophilin and its derivatives showed significant antiplatelet aggregation activity and vasorelaxing efrect. Furthermore, it displayed antioxidative activity equivalent to α-tocopherol.
All Science Journal Classification (ASJC) codes