Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles

Ronnie H. Fang; Che Ming J. Hu; Kevin N.H. Chen; Brian T. Luk; Cody W. Carpenter; Weiwei Gao; Shulin Li; Dong Er Zhang; Weiyue Lu; Liangfang Zhang

doi:10.1039/c3nr03064d

Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles

Ronnie H. Fang
, Che Ming J. Hu
, Kevin N.H. Chen
, Brian T. Luk
, Cody W. Carpenter
, Weiwei Gao
, Shulin Li
, Dong Er Zhang
, Weiyue Lu
, Liangfang Zhang

奈米醫學研究中心

研究成果: Article › 同行評審

285 引文斯高帕斯（Scopus）

摘要

RBC membrane-cloaked polymeric nanoparticles represent an emerging nanocarrier platform with extended circulation in vivo. A lipid-insertion method is employed to functionalize these nanoparticles without the need for direct chemical conjugation. Insertion of both folate and the nucleolin-targeting aptamer AS1411 shows receptor-specific targeting against model cancer cell lines.

原文	English
頁（從 - 到）	8884-8888
頁數	5
期刊	Nanoscale
卷	5
發行號	19
DOIs	https://doi.org/10.1039/c3nr03064d
出版狀態	Published - 2013 10月 7

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此研究成果有助於以下永續發展目標

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All Science Journal Classification (ASJC) codes

一般材料科學

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10.1039/c3nr03064d

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abstract = "RBC membrane-cloaked polymeric nanoparticles represent an emerging nanocarrier platform with extended circulation in vivo. A lipid-insertion method is employed to functionalize these nanoparticles without the need for direct chemical conjugation. Insertion of both folate and the nucleolin-targeting aptamer AS1411 shows receptor-specific targeting against model cancer cell lines.",

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AU - Fang, Ronnie H.

AU - Hu, Che Ming J.

AU - Chen, Kevin N.H.

AU - Luk, Brian T.

AU - Carpenter, Cody W.

AU - Gao, Weiwei

AU - Li, Shulin

AU - Zhang, Dong Er

AU - Lu, Weiyue

AU - Zhang, Liangfang

PY - 2013/10/7

Y1 - 2013/10/7

N2 - RBC membrane-cloaked polymeric nanoparticles represent an emerging nanocarrier platform with extended circulation in vivo. A lipid-insertion method is employed to functionalize these nanoparticles without the need for direct chemical conjugation. Insertion of both folate and the nucleolin-targeting aptamer AS1411 shows receptor-specific targeting against model cancer cell lines.

AB - RBC membrane-cloaked polymeric nanoparticles represent an emerging nanocarrier platform with extended circulation in vivo. A lipid-insertion method is employed to functionalize these nanoparticles without the need for direct chemical conjugation. Insertion of both folate and the nucleolin-targeting aptamer AS1411 shows receptor-specific targeting against model cancer cell lines.

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EP - 8888

JO - Nanoscale

JF - Nanoscale

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ER -

Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles

摘要

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