Manipulating T-junction chip for the generation of uniform O/W and W/O emulsions

Chia Hsien Yeh, Sheng Ji Lee, Meng Sun, Qun Fang, Yu-Cheng Lin

研究成果: Conference contribution

2 引文 斯高帕斯(Scopus)

摘要

The purpose of this study is to generate monodisperse oil-in-water (O/W) and water-in-oil (W/O) emulsions using microfluidic T-junction. The materials of poly methyl methacrylate (PMMA) (hydrophobic), polydimethylsiloxane (PDMS) (hydrophobic) and glass (hydrophilic) were employed for microfluidic chip fabrication. Our strategy is based on the shear focus effect and sheath effect (focusing) to form uniform self-assembling sphere structures, the so-called O/W and W/O emulsions, in the T-junction microchannel. Results show that the size from 31 μm to 43 μm in diameter of O/W emulsions was generated by using the glass-based microfluidic chip. In addition, results show that the size from 70 μm to 220 μm of W/O emulsions was available by utilizing the PMMA-based microfluidic chip. These W/O emulsions were further applied to Ca-alginate microparticles (Ca-alg MPs). And the results also show that the size from 410 μm to 700 μm of UV-Photopolymerized microparticles was available by utilizing the PDMS-based microfluidic chip. The proposed microfluidic chips are capable of generating relatively uniform micro-droplets and have the advantages of actively controlling the droplet diameter, and having a simple and low cost process, with a high throughput.

原文English
主出版物標題Microfluidics, BioMEMS, and Medical Microsystems VI
DOIs
出版狀態Published - 2008 三月 31
事件Microfluidics, BioMEMS, and Medical Microsystems VI - San Jose, CA, United States
持續時間: 2008 一月 212008 一月 22

出版系列

名字Proceedings of SPIE - The International Society for Optical Engineering
6886
ISSN(列印)0277-786X

Other

OtherMicrofluidics, BioMEMS, and Medical Microsystems VI
國家/地區United States
城市San Jose, CA
期間08-01-2108-01-22

All Science Journal Classification (ASJC) codes

  • 電子、光磁材料
  • 凝聚態物理學
  • 電腦科學應用
  • 應用數學
  • 電氣與電子工程

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