Mechanobiology and Mechanotherapy for Skin Disorders

Chao Kai Hsu, Rei Ogawa

研究成果: Chapter

摘要

Human skin is the largest organ of the body. During growth and development, the skin expands to cover the growing skeleton and soft tissues by constantly responding to the intrinsic forces of underlying skeletal growth. In addition, it responds to the extrinsic forces generated by body movements and external mechanical stimuli. Therefore, mechanobiology plays an important role in skin biology and disease pathogenesis. In this chapter, we will review the skin structure, the skin receptors for mechanical forces, and the skin disorders associated with mechanobiological dysfunction, such as keloid, scleroderma, pincer nails, bullous pemphigoid, Ehlers-Danlos syndrome (EDS), cutis laxa, skin aging, diabetic skin ulcers, leprosy, and lymphedema. Lastly, we will present a short review of mechanotherapy and its future development.

原文English
主出版物標題Mechanobiology
主出版物子標題Exploitation for Medical Benefit
發行者wiley
頁面221-237
頁數17
ISBN(電子)9781118966174
ISBN(列印)9781118966143
DOIs
出版狀態Published - 2016 十一月 7

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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