Melanocyte Detection and Intercellular Distribution Analysis of Melasma in Harmonically Generated Microscopy Images

Gwo-Giun Lee, Hsien Pin Chu, Chi Kuang Sun, Yi Hua Liao

研究成果: Conference contribution

摘要

Melasma is the common hyperpigmentary skin disorder that can cause bright and dark brown macules and patches on sun-exposed areas of the skin owing to hyperactivity of epidermal melanocytes. Correspondingly, melanocyte detection and subsequent observation are principle procedures conducted by physicians. In this paper, we utilize methodology of contextual comparison based on intrinsic cell characteristics to detect epidermal melanocytes, which can provide consistent and accurate results for assisting the assessment of diagnosis. In addition, we propose the method of Computer-Aided Diagnosis (CAD) via moving window statistical analysis, which evaluate the relationship between detected melanocytes and the characteristics of the intercellular distribution in the Third Harmonic Generation (THG) image. The experimental results show the inconsistent distribution of cells around melanocytes in different disease categories, while processing of an adequate number of in vivo virtual biopsy images provides quantitative and objective bio-information.

原文English
主出版物標題2018 International Conference on Orange Technologies, ICOT 2018
編輯Abba Suganda Girsang, Emil R. Kaburuan
發行者Institute of Electrical and Electronics Engineers Inc.
ISBN(電子)9781538673195
DOIs
出版狀態Published - 2018 七月 2
事件6th International Conference on Orange Technologies, ICOT 2018 - Bali, Indonesia
持續時間: 2018 十月 232018 十月 26

出版系列

名字2018 International Conference on Orange Technologies, ICOT 2018

Conference

Conference6th International Conference on Orange Technologies, ICOT 2018
國家/地區Indonesia
城市Bali
期間18-10-2318-10-26

All Science Journal Classification (ASJC) codes

  • 電腦網路與通信

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