Metastatic squamous cell carcinoma resembling angiosarcoma complicating dystrophic epidermolysis bullosa

J. A. McGrath, O. M.V. Schofield, B. J. Mayou, P. H. McKee, R. A.J. Eady

研究成果: Article同行評審

25 引文 斯高帕斯(Scopus)

摘要

We report a patient with generalized recessive dystrophic epidermolysis bullosa (RDEB) who developed 3 squamous cell carcinomas. The tumours appeared simultaneously at acral sites on both upper limbs and were poorly differentiated. Despite surgery and radiotherapy the patient died from metastatic disease within 6 months of presentation. This case highlights many of the typical features of this complication of RDEB, including the overall poor prognosis. Of particular interest was the histology of one of the tumours which caused diagnostic difficulties: haematoxylin and eosin staining suggested an angiosarcomatous pathology, but the use of immunocytochemistry proved that the tumour was a squamous cell carcinoma in origin.

原文English
頁(從 - 到)235-238
頁數4
期刊Dermatology
182
發行號4
DOIs
出版狀態Published - 1991

All Science Journal Classification (ASJC) codes

  • 皮膚科

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