Mild cell disruption methods for bio-functional proteins recovery from microalgae—Recent developments and future perspectives

Win Nee Phong, Pau Loke Show, Tau Chuan Ling, Joon Ching Juan, Eng Poh Ng, Jo Shu Chang

研究成果: Article同行評審

38 引文 斯高帕斯(Scopus)

摘要

Bio-functional proteins from microalgae have numerous biological properties with health-promoting effects. However, efficient harnessing of bio-functional proteins from microalgae is still in its infancy. One of the major obstacles that hinder the mass production of bio-functional proteins is the presence of resistant cell wall that diminishes the liberation of cell contents. As the bio-functional proteins are very sensitive to denaturation, selecting a mild disruption method to rupture the cell wall, while preserving their bioactivity and functionality, is of vital importance in downstream processing. To ensure the future development of efficient mild disruption methods for maximum recovery of bio-functional proteins from microalgae, this review provides useful information on various mild disruption approaches, current status, potential technologies that are still under development, as well as their advantages and constraints. In particular, those potential technologies that require further attention in the future (namely, explosive decompression, microfluidization, pulsed arc technology and cationic polymer coated membranes) are also discussed in this review.

原文English
頁(從 - 到)506-516
頁數11
期刊Algal Research
31
DOIs
出版狀態Published - 2018 四月

All Science Journal Classification (ASJC) codes

  • 農學與作物科學

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