@article{d709ba0cd00b4aa1818162b93f9d5a44,
title = "Mobile healthcare system based on the combination of a lateral flow pad and smartphone for rapid detection of uric acid in whole blood",
abstract = "Excessive production of uric acid (UA) in blood may lead to gout, hyperuricaemia and kidney disorder; thus, a fast, simple and reliable biosensor is needed to routinely determine the UA concentration in blood without pretreatment. The purpose of this study was to develop a mobile healthcare (mHealth) system using a drop of blood, which comprised a lateral flow pad (LFP), mesoporous Prussian blue nanoparticles (MPBs) as artificial nanozymes and auto-calculation software for on-site determination of UA in blood and data management. A standard curve was found to be linear in the range of 1.5–8.5 mg/dL UA, and convenience, cloud computing and personal information management were simultaneously achieved for the proposed mHealth system. Our mHealth system appropriately met the requirements of application in patients{\textquoteright} homes, with the potential of real-time monitoring by their primary care physicians (PCPs).",
author = "Li, {Nan Si} and Chen, {Ying Tzu} and Hsu, {Ying Pei} and Pang, {Hao Han} and Huang, {Chiung Yin} and Shiue, {Yow Ling} and Wei, {Kuo Chen} and Yang, {Hung Wei}",
note = "Funding Information: This work was financially supported by the Ministry of Science and Technology , Chang Gung Memorial Hospital , and National Health Research Institutes , Taiwan (R.O.C.), for the financial assistance provided ( MOST106-2628-E-110-001-MY3 , MOST106-2628-B-110-001-MY4 , CORPG3K0091 , and NHRI-EX108-10502NI ). We would also like to thank the Chang Gung Memorial Hospital Microscopy Core Laboratory for their assistance with the TEM, SEM, and EDS techniques. Funding Information: This work was financially supported by the Ministry of Science and Technology, Chang Gung Memorial Hospital, and National Health Research Institutes, Taiwan (R.O.C.), for the financial assistance provided (MOST106-2628-E-110-001-MY3, MOST106-2628-B-110-001-MY4, CORPG3K0091, and NHRI-EX108-10502NI). We would also like to thank the Chang Gung Memorial Hospital Microscopy Core Laboratory for their assistance with the TEM, SEM, and EDS techniques. Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",
year = "2020",
month = sep,
day = "15",
doi = "10.1016/j.bios.2020.112309",
language = "English",
volume = "164",
journal = "Biosensors and Bioelectronics",
issn = "0956-5663",
publisher = "Elsevier Limited",
}